Ishitoya T, Sato S, DiBenedetto G, Mohri H, Merendino A, Dillard D H
Ann Thorac Surg. 1977 Jan;23:52-7. doi: 10.1016/s0003-4975(10)64069-6.
The effect of halothane-100% oxygen anesthesia on oxygen consumption was studied in 10 dogs subjected to surface-induced deep hypothermia with 30 minutes of circulatory arrest. The results were compared with previous oxygen consumtion data under ether-100% oxygen anesthesia. Low cardiac output, especially during the rewarming period, low PaO2, and a large arteriovenous oxygen difference during rewarming were significantly different in the halothane group, despite identical oxygen consumption in both groups. These differences could not elucidate the exact cause of postoperative motor disturbances associated with 30 minutes of circulatory arrest in the halothane group. The possibility that there was higher oxygen consumption under halothane anesthesia is discussed.
对10只狗进行体表诱导深度低温并循环阻断30分钟，研究了氟烷-100%氧气麻醉对氧消耗的影响。将结果与之前在乙醚-100%氧气麻醉下的氧消耗数据进行了比较。尽管两组的氧消耗相同，但氟烷组的心输出量较低，尤其是在复温期，动脉血氧分压较低，且复温期动静脉氧分压差较大，这些差异显著。这些差异无法阐明氟烷组中与30分钟循环阻断相关的术后运动障碍的确切原因。文中讨论了氟烷麻醉下氧消耗较高的可能性。
