Coggon D, Wield G
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, United Kingdom.
Scand J Work Environ Health. 1993 Apr;19(2):85-8. doi: 10.5271/sjweh.1493.
The possible hazard of lung cancer among cooks was studied in a cohort of 1798 cooks who had retired from the Army Catering Corps and 1310 referents retired from the Royal Army Pay Corps. During the follow-up from 1974 to 1989 the mortality of the referents was similar to that of the national population, apart from a moderate increase in lung cancer [standardized mortality ratio (SMR) 1.38]. Mortality from lung cancer among the cooks was significantly higher than among the national population [SMR 1.82, 95% confidence interval (95% CI) 1.25-2.57], as was mortality from cancer of the large intestine (SMR 3.03), ischemic heart disease (SMR 1.42), cerebrovascular disease (SMR 2.05), and digestive disease (SMR 2.27). The high rate of lung cancer among the cooks supports the hypothesis of an occupational hazard, although at least part of the excess was probably due to smoking. Possible explanations for the elevated mortality from other diseases include poor nutrition in early life, smoking, and high consumption of alcohol.
在一个由1798名从陆军餐饮部队退休的厨师和1310名从皇家陆军薪资部队退休的对照人员组成的队列中,研究了厨师患肺癌的潜在风险。在1974年至1989年的随访期间,对照人员的死亡率与全国人口的死亡率相似,但肺癌死亡率有适度增加[标准化死亡比(SMR)为1.38]。厨师中的肺癌死亡率显著高于全国人口[SMR为1.82,95%置信区间(95%CI)为1.25 - 2.57],结肠癌死亡率(SMR为3.03)、缺血性心脏病死亡率(SMR为1.42)、脑血管疾病死亡率(SMR为2.05)和消化系统疾病死亡率(SMR为2.27)也是如此。厨师中肺癌的高发病率支持了职业危害这一假设,尽管至少部分超额发病率可能归因于吸烟。其他疾病死亡率升高的可能解释包括早年营养状况差、吸烟和高酒精摄入量。