Therapies directed against endotoxin--has the time come?
作者信息
Quezado Z M, Hoffman W D
出版信息
West J Med. 1993 Apr;158(4):424-5.
Abstract
摘要
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Therapies directed against endotoxin--has the time come?针对内毒素的疗法——时机到了吗？
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本文引用的文献
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Monoclonal antibodies to endotoxin in the management of sepsis.用于脓毒症治疗的抗内毒素单克隆抗体。
West J Med. 1993 Apr;158(4):393-9.
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Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock.犬类的内毒素和肿瘤坏死因子激发试验模拟了人类感染性休克的心血管特征。
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Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies.抗脂多糖（LPS）抗体的保护效力与LPS诱导的肿瘤坏死因子α及白细胞介素6抑制之间的关联。O侧链特异性抗体与核心LPS抗体的比较。
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Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents.静脉注射内毒素后正常人体内白细胞介素8和肿瘤坏死因子的检测：抗炎药物的作用
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Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group.使用抗内毒素的HA-1A人单克隆抗体治疗革兰氏阴性菌血症和感染性休克。一项随机、双盲、安慰剂对照试验。HA-1A脓毒症研究组。
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Endotoxemia in human septic shock.人类脓毒症休克中的内毒素血症
Chest. 1991 Jan;99(1):169-75. doi: 10.1378/chest.99.1.169.
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Immunotherapy with antibodies to core lipopolysaccharide: a critical appraisal.使用抗核心脂多糖抗体的免疫疗法：批判性评估。
Infect Dis Clin North Am. 1991 Dec;5(4):915-27.
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