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[大鼠幼崽中与年龄相关的运动兴奋脊髓发生器抑制的可能途径]

[The possible pathways of age-related inhibition of the spinal generators of motor excitation in rat pups].

作者信息

Bursian A V, Semenova Iu O, Vdovichenko N D

出版信息

Zh Evol Biokhim Fiziol. 1993 Mar-Apr;29(2):215-8.

PMID:8317185
Abstract

In experiments on rat puppies, it has been demonstrated that cutting the dorsal part of the spinal cord at the 10th day of postnatal life results at the 17-18th day in a relative hyperactivity, which is revealed in significantly higher volume of the spontaneous motor activity, duration and number of discharges, as well as in significant facilitation of reactions of late discharge type. Therefore, in rat puppies, the pathways of age inhibition of the activity of spinal pacemakers of motor excitation are located in dorsal and dorsolateral parts of the spinal cord.

摘要

在对新生大鼠幼犬的实验中,已证明在出生后第10天切断脊髓的背侧部分,会在第17 - 18天导致相对多动,这表现为自发运动活动的量显著增加、放电的持续时间和次数显著增加,以及晚期放电类型反应的显著易化。因此,在新生大鼠幼犬中,运动兴奋的脊髓起搏器活动的年龄抑制通路位于脊髓的背侧和背外侧部分。

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