Kuznetsov S V
Zh Evol Biokhim Fiziol. 1993 Sep-Dec;29(5-6):565-73.
In experiments on rat puppies of the first month of postnatal life, under the conditions of real motor behaviour (spontaneous periodic motor activity) and the evoked motor reactions (late prolonged motor discharges), studies have been made on the development of coordination relationships between antagonists of the same extremity and between homologous muscles of the hindlimbs. In was found that irrespectively of the early onset of reciprocal excitation of antagonists, the mechanisms of this activity are not mature. Maturation of bilateral coordinations takes place at later stages. It was noted that one of the hemicenters of the spinal motor pacemaker is capable of producing rhythmic or constant activity which is not related to the pattern of the activity in the other hemicenters of the pacemaker of the same extremity or hemicenters of pacemaker of homologous extremity. Administration of DOPA causes the disturbance of coordination relationships.
在对出生后第一个月的新生大鼠幼犬进行的实验中，在真实运动行为（自发周期性运动活动）和诱发运动反应（延迟延长运动放电）的条件下，研究了同一肢体拮抗肌之间以及后肢同源肌肉之间协调关系的发展。发现不管拮抗肌的相互兴奋出现得有多早，这种活动的机制都不成熟。双侧协调的成熟发生在后期阶段。值得注意的是，脊髓运动起搏器的一个半中枢能够产生有节律的或持续的活动，这种活动与同一肢体起搏器的其他半中枢或同源肢体起搏器的半中枢的活动模式无关。给予多巴会导致协调关系紊乱。
