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[大鼠幼崽节段性传入神经刺激期间的晚期延长运动放电:与年龄相关的特征]

[The late prolonged motor discharges during stimulation of the segmentary afferents in rat pups: the age-related characteristics].

作者信息

Kuznetsov S V, Bursian A V

出版信息

Zh Evol Biokhim Fiziol. 1990 May-Jun;26(3):362-8.

PMID:2220205
Abstract

In experiments on intact 5-30-day rat puppies under slight urethane narcosis, stimulation of contralateral afferents evoked late prolonged discharges in extensor muscles. Apart from these discharges, studies were also made on the outbursts of autogenic periodic motor activity. The specific feature of late discharges within the first 10 days is their extreme duration and the presence of rhythmic components. With respect to the pattern and temporal parameters, there is a strong similarity between late discharges and autogenic periodic motor activity which is typical of newborn rats. The decrease in the intensity of late discharges in ontogenesis is paralleled by inhibition of autogenic activity. The data obtained indicate that late discharges are genetically related to the ancient property of the central nervous system, i.e. the capacity to self-excitation and maintenance of active state.

摘要

在轻度乌拉坦麻醉下,对5至30日龄完整的幼鼠进行实验,刺激对侧传入神经会在伸肌中诱发晚期延长放电。除了这些放电外,还对自发周期性运动活动的爆发进行了研究。前10天内晚期放电的具体特征是其持续时间极长且存在节律成分。就模式和时间参数而言,晚期放电与新生大鼠典型的自发周期性运动活动之间存在很强的相似性。个体发育过程中晚期放电强度的降低与自发活动的抑制同时出现。所获得的数据表明,晚期放电在遗传上与中枢神经系统的古老特性有关,即自我兴奋和维持活跃状态的能力。

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