Wickman M, Nordvall S L, Pershagen G, Korsgaard J, Johansen N
Department of Environmental Health and Infectious Diseases Control, Karolinska Hospital, Stockholm, Sweden.
Am Rev Respir Dis. 1993 Jul;148(1):58-62. doi: 10.1164/ajrccm/148.1.58.
Factors favoring sensitization to house dust mites (HDM) were studied in a cold, temperate climate in northern Sweden. Sixty-five children previously found to react positively to a skin prick test (SPT) to HDM were included. The SPT to HDM was repeated, and serum IgE antibodies to D. pteronyssinus and D. farinae were determined. HDM, Euroglyphus maynei, Tarsonemus, or storage mites occurred in mattress dust samples from 23 of the 65 homes, and in 10 homes more than 100 HDM/g of mattress dust were found. Mites were more prevalent in mattress dust from the basement and ground levels than from the upper floors. Sensitization to HDM was strongly with the presence of domestic mites in mattress and floor dust. Previous longer stays in southern Sweden or Europe were also associated with present sensitization to HDM, and this was independent of occurrence of mites in the residence. The results indicate that HDM growth and potential for sensitization in cold, temperate regions is highly dependent on the microhabitat, and that sensitization to HDM should be possible to prevent in such climatic regions.
在瑞典北部寒冷的温带气候地区，对有利于屋尘螨（HDM）致敏的因素进行了研究。纳入了65名先前对HDM皮肤点刺试验（SPT）反应呈阳性的儿童。重复进行HDM的SPT，并测定血清中针对粉尘螨和屋尘螨的IgE抗体。在65户家庭中的23户床垫灰尘样本中发现了HDM、梅氏嗜霉螨、跗线螨或仓储螨，10户家庭的床垫灰尘中每克发现超过100只HDM。地下室和地面层床垫灰尘中的螨虫比上层更普遍。对HDM的致敏与床垫和地板灰尘中存在家养螨虫密切相关。以前在瑞典南部或欧洲停留时间较长也与目前对HDM的致敏有关，这与住所中螨虫的出现无关。结果表明，在寒冷的温带地区，HDM的生长和致敏可能性高度依赖于微生境，并且在这种气候区域应该有可能预防对HDM的致敏。
