Nespoli A, Ravizzini C, Trivella M, Segala M
Department of Emergency Surgery, Centro E. Palini e G. Bevilacqua, Universita di Milano, Italy.
Arch Surg. 1993 Jul;128(7):814-8. doi: 10.1001/archsurg.1993.01420190110014.
Because the choice of surgical procedure for colonic perforation is still matter of debate, we retrospectively studied peritonitis caused by spontaneous colonic perforation to assess predictors of mortality and the safety of primary resection and anastomosis.
Case series.
We investigated one hundred thirty-six consecutive patients with peritonitis due to colonic perforation who were surgically treated in an emergency surgery department. Eighty-one patients underwent primary resection and anastomosis, thirty-three underwent the Hartmann procedure, and twenty-two had simple colostomy. The seriousness of peritonitis was assessed in terms of Hinchey stage, the Mannheim Peritonitis Index (MPI), and the acute physiology and chronic health evaluation (APACHE) II score.
The overall mortality rate was 20%. The APACHE II scores and MPIs were lower for survivors than for nonsurvivors. The mortality rate was 6% for primary resection and anastomosis, 30% for the Hartmann procedure, and 59% for simple colostomy, but the severity scores were significantly lower in patients who underwent primary resection than those of patients who had the Hartmann procedure and colostomy, respectively.
Since primary resection and anastomosis has been shown to be safe, we suggest that is is proper, even in the presence of peritonitis. In spite of this, we conclude that the surgical procedure does not influence outcome but that the mortality rate is related to the severity of peritonitis, accurately measured by APACHE II score and MPI.
由于结肠穿孔手术方式的选择仍存在争议,我们回顾性研究了自发性结肠穿孔所致腹膜炎,以评估死亡率的预测因素以及一期切除吻合术的安全性。
病例系列研究。
我们调查了136例因结肠穿孔导致腹膜炎并在急诊外科接受手术治疗的连续病例。81例行一期切除吻合术,33例行Hartmann手术,22例行单纯结肠造口术。根据Hinchey分期、曼海姆腹膜炎指数(MPI)和急性生理与慢性健康状况评估(APACHE)II评分评估腹膜炎的严重程度。
总死亡率为20%。幸存者的APACHE II评分和MPI低于非幸存者。一期切除吻合术的死亡率为6%,Hartmann手术为30%,单纯结肠造口术为59%,但接受一期切除的患者的严重程度评分分别显著低于接受Hartmann手术和结肠造口术的患者。
由于一期切除吻合术已被证明是安全的,我们建议即使存在腹膜炎,该手术也是合适的。尽管如此,我们得出结论,手术方式并不影响预后,但死亡率与腹膜炎的严重程度相关,可通过APACHE II评分和MPI准确测量。