Myers S I, Valentine R J, Estrera A, Clagett G P
Department of Surgery, University of Texas Southwestern Medical Center, Tex. 75235-9031.
Ann Vasc Surg. 1993 May;7(3):239-42. doi: 10.1007/BF02000248.
Five patients with severe symptomatic carotid and coronary artery disease were treated with staged carotid endarterectomy and coronary artery bypass grafting (CABG) under the protection of an intra-aortic balloon pump (IABP) over a 56-month period. All patients presented with unstable angina and multiple ipsilateral transient ischemic attacks. Two of the four patients had four previous myocardial infarctions. Arteriography demonstrated three-vessel coronary artery disease and 80% to 95% stenosis of the ipsilateral internal carotid artery in all patients. An IABP was placed prior to uneventful carotid endarterectomy performed with vein patch angioplasty (three patients) or primary closure (two patients) under general anesthesia. All five patients had remarkably stable blood pressure and cardiac outputs while on the IABP. Twenty-four hours after carotid endarterectomy the patients underwent uneventful CABG of three or more vessels. No complications occurred with either surgical procedure. One patient required femoral embolectomy and repair of a small false femoral aneurysm following removal of the IABP. All patients were discharged home 7 to 13 days after CABG. This initial report suggests that IABP can be used safely in staged operations for carefully selected patients with unstable angina and severe symptomatic carotid artery disease.
在56个月的时间里,对5例患有严重症状性颈动脉和冠状动脉疾病的患者,在主动脉内球囊反搏(IABP)的保护下,分期进行颈动脉内膜切除术和冠状动脉旁路移植术(CABG)。所有患者均表现为不稳定型心绞痛和多次同侧短暂性脑缺血发作。4例患者中有2例曾有过4次心肌梗死。血管造影显示所有患者均患有三支冠状动脉疾病,同侧颈内动脉狭窄80%至95%。在全身麻醉下,于顺利完成的颈动脉内膜切除术(3例患者采用静脉补片血管成形术,2例患者采用一期缝合)之前放置IABP。所有5例患者在使用IABP期间血压和心输出量均显著稳定。颈动脉内膜切除术后24小时,患者顺利接受了三支或更多支血管的CABG。两种手术均未发生并发症。1例患者在移除IABP后需要进行股动脉取栓术并修复一个小的股部假性动脉瘤。所有患者在CABG后7至13天出院。这份初步报告表明,对于精心挑选的不稳定型心绞痛和严重症状性颈动脉疾病患者,IABP可安全用于分期手术。