Allie D E, Lirtzman M, Malik A P, Kowalski J M, Barker E A, Walker C M
Cardiovascular Institute of the South, Columbia Medical Center of Southwest Louisiana, Lafayette 70596-1160, USA.
Ann Thorac Surg. 1998 Oct;66(4):1230-5. doi: 10.1016/s0003-4975(98)00841-8.
Few reports address the high-risk patient population with concomitant critical carotid and left main coronary disease with left ventricular dysfunction. To decrease the risks involved with the simultaneous and traditional staged surgical approaches, we developed a rapid staging strategy using an intraaortic balloon pump.
Between 1992 and 1996, 20 patients presented with a high-risk "triad" defined by greater than 70% stenosis of the left main coronary artery, ejection fraction less than 0.30, and greater than 90% stenosis of the internal carotid artery. An intraaortic balloon pump was placed immediately before carotid endarterectomy under angiographic guidance. Less than 24 hours later (mean, 18 hours) coronary artery bypass grafting was performed, and the intraaortic balloon pump was removed the day of coronary artery bypass grafting in all cases (total IABP duration, <36 hours).
Eighteen patients (18/20) were extubated on the day of coronary artery bypass grafting (mean, 12 hours). Sixteen patients (16/20) were transferred from the intensive care unit within 48 hours, with total hospital stay ranging from 6 to 12 days (mean, 8 days). There were no 30-day postoperative deaths, myocardial infarctions, or neurologic, vascular, bleeding, or other major complications. At a mean 29.4-month follow-up, there were two noncardiac deaths and no neurologic events. Six-month, 1-year, and 2-year follow-up ultrasounds showed all operative carotid arteries remained patent.
A rapid staged procedure with angiographically guided placement of the intraaortic balloon pump was safe and effective in this very high risk patient population. It may be an option to decrease the risks involved with simultaneous operations and increase the efficiency and safety of "traditional" staged carotid and coronary artery bypass grafting procedures.
很少有报告涉及伴有严重颈动脉和左主干冠状动脉疾病且左心室功能不全的高危患者群体。为降低同时进行和传统分期手术方法所涉及的风险,我们开发了一种使用主动脉内球囊泵的快速分期策略。
1992年至1996年间,20例患者表现出由左主干冠状动脉狭窄大于70%、射血分数小于0.30以及颈内动脉狭窄大于90%所定义的高危“三联征”。在血管造影引导下,于颈动脉内膜切除术之前立即置入主动脉内球囊泵。不到24小时后(平均18小时)进行冠状动脉旁路移植术,所有病例在冠状动脉旁路移植术当天移除主动脉内球囊泵(主动脉内球囊泵总使用时间<36小时)。
18例患者(18/20)在冠状动脉旁路移植术当天(平均12小时)拔管。16例患者(16/20)在48小时内从重症监护病房转出,总住院时间为6至12天(平均8天)。术后30天内无死亡、心肌梗死或神经、血管、出血或其他重大并发症。平均随访29.4个月时,有2例非心脏性死亡,无神经事件。6个月、1年和2年的随访超声显示所有手术的颈动脉均保持通畅。
在这一极高危患者群体中,通过血管造影引导放置主动脉内球囊泵的快速分期手术是安全有效的。它可能是一种降低同时手术风险并提高“传统”分期颈动脉和冠状动脉旁路移植术效率和安全性的选择。