Lopes J M, Schulze K L, Yates J W, Hirsch J P, Henry S A
Department of Molecular and Cellular Biochemistry, Stritch School of Medicine, Loyola University, Chicago, Maywood, Illinois 60153.
J Bacteriol. 1993 Jul;175(13):4235-8. doi: 10.1128/jb.175.13.4235-4238.1993.
The INO1 promoter of Saccharomyces cerevisiae includes a copy of an upstream repression sequence (URS1; 5'AGCCGCCGA 3') observed in the promoters of several unrelated yeast genes. Expression of INO1-lacZ and CYC1-lacI'Z, activated by the INO1 UASINO, is significantly decreased by the INO1 URS1.
酿酒酵母的INO1启动子包含一个在几个不相关酵母基因的启动子中观察到的上游阻遏序列(URS1;5'AGCCGCCGA 3')的拷贝。由INO1 UASINO激活的INO1-lacZ和CYC1-lacI'Z的表达被INO1 URS1显著降低。