Newton J, Illingworth R, Elias J, McEwan J
Br Med J. 1977 Jan 22;1(6055):197-9. doi: 10.1136/bmj.1.6055.197.
A total of 1245 women had a copper 7 intrauterine contraceptive device (IUD) inserted in 1971-3 were followed up for three years (22 761-5 women months of use). After 24 months 483 women elected to continue with the same copper 7 (continuation group), and 183 had their copper 7 replaced with a new one (replacement group). The subsequent pregnancy and expulsion rates were both significantly lower in the replacement group. The higher pregnancy rate among the women who continued to use their copper 7 device for a third year suggests that although the copper is still there, it is not available for contraceptive action. Replacing the device at 24 months did not seem to cause again the problems that usually occur in the first six months of IUD use.
1971年至1973年间,共有1245名女性植入了铜7宫内节育器(IUD),并随访了三年(使用时间总计22761.5女性月)。24个月后,483名女性选择继续使用同一枚铜7(继续使用组),183名女性将其铜7换成了新的(更换组)。更换组随后的妊娠率和脱落率均显著更低。继续使用铜7装置三年的女性中较高的妊娠率表明,尽管铜仍在,但无法起到避孕作用。在24个月时更换装置似乎并未再次引发通常在使用IUD的前六个月出现的问题。