铜T 220C：一种新型长效宫内铜节育器。

The Copper T 220C: a new long-acting copper intrauterine contraceptive device.

作者信息

Cooper D L, Millen A K, Mishell D R

出版信息

Am J Obstet Gynecol. 1976 Jan 15;124(2):121-4. doi: 10.1016/s0002-9378(16)33285-9.

Abstract

The Copper T(TCu) intrauterine contraceptive device (IUD) has been found to be an effective method of contraception but has the disadvantage of needing periodic replacement due to loss of copper through dissolution and fragmentation of the copper wire. Modification of the Copper T to overcome this disadvantage involved substitution of copper sleeves for wire on the vertical arm and the addition of copper sleeves to the horizonal arms to give an effective surface area of 220 sq. mm. of copper and an estimated life span of 20 years. A randomized comparative study was undertaken in 999 women to determine if the new model performed as well as the wire-wound Copper T 300. Net cumulative first-event rates at one year were as follows: TCu 220C-pregnancy 0.9, expulsion 3.7, removal for pain or bleeding 14.4; TCu 300-pregnancy 1.1, expulsion 3.1, removal for pain or bleeding 9.3. None of the differences in event rates were significant. If long-term follow-up confirms these findings, this new long-lasting copper intrauterine device could become the IUD of choice for all women.

摘要

铜T（TCu）宫内节育器（IUD）已被证明是一种有效的避孕方法，但由于铜丝的溶解和断裂导致铜流失，需要定期更换，这是其缺点。对铜T进行改进以克服这一缺点，方法是在垂直臂上用铜套代替铜丝，并在水平臂上增加铜套，使铜的有效表面积达到220平方毫米，估计使用寿命为20年。对999名女性进行了一项随机对照研究，以确定新模型的性能是否与绕丝铜T 300相同。一年时的净累积首次事件发生率如下：TCu 220C-妊娠0.9%，排出3.7%，因疼痛或出血取出14.4%；TCu 300-妊娠1.1%，排出3.1%，因疼痛或出血取出9.3%。事件发生率的差异均无统计学意义。如果长期随访证实这些结果，这种新型长效铜宫内节育器可能会成为所有女性的首选IUD。