Langøen A, Vik H, Nyfors A
Medisinsk avdeling, Fylkessjukehuset i Haugesund.
Tidsskr Nor Laegeforen. 1993 May 30;113(14):1712-5.
Diaper dermatitis is a multifactorial dermatological disorder characterized by inflammation in the diaper area. About half of all babies and old people in need of care experience light dermatitis, while 20% have moderate and 5% severe dermatitis. Friction from the diaper, occlusion, irritation from faeces, ammonia, detergents, candida albicans, proteolytic and lipolytic enzymes and moisture deposited on the epidermis cause damage at the stratum corneum layer of the epidermis. Diaper dermatitis is caused by a combination of mostly irritant effects. Compounds that infiltrate the skin can aggravate the reaction to the damaged epidermis. The barrier function of epidermis must be restored in order to prevent and treat diaper dermatitis.
尿布皮炎是一种多因素导致的皮肤病，其特征为尿布区域出现炎症。所有需要护理的婴儿和老年人中，约一半会经历轻度皮炎，20%有中度皮炎，5%有重度皮炎。尿布的摩擦、闭塞、粪便、氨、洗涤剂、白色念珠菌、蛋白水解酶和脂肪分解酶的刺激以及沉积在表皮上的水分会导致表皮角质层受损。尿布皮炎主要是由多种刺激作用共同引起的。渗入皮肤的化合物会加重对受损表皮的反应。为了预防和治疗尿布皮炎，必须恢复表皮的屏障功能。
