Prato F S, Kurdyak R, Saibil E A, Carruthers J S, Rider W D, Aspin N
Cancer. 1977 Jan;39(1):71-8. doi: 10.1002/1097-0142(197701)39:1<71::aid-cncr2820390114>3.0.co;2-f.
The incidence of radiation pneumonitis was determined in 43 patients following a single fraction half body (UHB) irradiation. Radiographs taken before and at least 4 months after UHB treatment were scored for evidence of pneumonitis. Nine patients received only pulmonary irradiation from the UHB treatment. There was no evidence of radiation pneumonitis in eight for whom there was adequate follow up. From this and other supportive evidence presented in this retrospective study, it is suggested that a total lung irradiation of 800 rads produces no changes that can be seen radiographically, provided there has been no previous major pulmonary irradiation or concurrent malignant pulmonary disease. In patients who received additional mediastinal irradiation, severe changes appeared within this field while mild to moderate radiographic changes were seen outside the mediastinal field.
对43例接受单次半身(UHB)照射的患者进行放射性肺炎发病率的测定。在UHB治疗前及治疗后至少4个月拍摄的X线片进行评分,以判断是否存在肺炎迹象。9例患者仅接受了UHB治疗中的肺部照射。在有充分随访的8例患者中未发现放射性肺炎迹象。从这项回顾性研究提供的这一证据及其他支持性证据来看,提示若此前没有过主要的肺部照射或并发恶性肺部疾病,800拉德的全肺照射不会产生X线可见的变化。在接受额外纵隔照射的患者中,该照射野内出现了严重变化,而纵隔野以外可见轻度至中度的X线变化。