Coppola M P, Lawee M
Department of Medicine, Mercy Hospital, Springfield, Mass.
Chest. 1993 Jul;104(1):19-25. doi: 10.1378/chest.104.1.19.
Unattended four-channel sleep apnea recording has been shown to be an accurate tool in the diagnosis of moderate to severe obstructive sleep apnea. We selected 11 patients with severe obstructive sleep apnea who had an apnea-hypopnea index (AHI) determined by unattended sleep apnea recording. The mean AHI was 41 (SD, 17.5). We began nasal continuous positive airway pressure (NCPAP) at home empirically with 5 cm to 7.5 cm of pressure for several nights. We then adjusted the level of NCPAP after telephone interview with the patients and their significant others. The level of NCPAP was increased by 2.5-cm increments until the patients reported cessation of snoring and symptom improvement. The mean NCPAP was 8.0 cm (SD, 1.4). We repeated the overnight sleep apnea recording while on NCPAP in all patients at home to determine their response to therapy. All 11 patients had documented return of their AHI to normal (mean AHI, 2.4; SD, 1.6). Statistically significant improvement was noted in the number of obstructive apneas, hypopneas, total respiratory events, and the AHI. Follow-up data confirmed that patients had improvement in their symptoms and remained compliant with therapy (mean follow-up = 18 months; SD, 10.2). No serious complications were encountered when NCPAP was introduced in an unattended setting. We were able to diagnose and treat these patients in an entirely outpatient setting.
无人值守的四通道睡眠呼吸暂停记录已被证明是诊断中度至重度阻塞性睡眠呼吸暂停的一种准确工具。我们选择了11例通过无人值守睡眠呼吸暂停记录确定呼吸暂停低通气指数(AHI)的重度阻塞性睡眠呼吸暂停患者。平均AHI为41(标准差,17.5)。我们在家中经验性地开始使用鼻持续气道正压通气(NCPAP),压力为5厘米至7.5厘米,持续数晚。然后在与患者及其重要他人进行电话访谈后调整NCPAP水平。NCPAP水平以2.5厘米的增量增加,直到患者报告打鼾停止且症状改善。平均NCPAP为8.0厘米(标准差,1.4)。我们让所有患者在家中使用NCPAP时重复夜间睡眠呼吸暂停记录,以确定他们对治疗的反应。所有11例患者的AHI均恢复正常(平均AHI,2.4;标准差,1.6)。在阻塞性呼吸暂停、低通气、总呼吸事件数量以及AHI方面均有统计学上的显著改善。随访数据证实患者症状有所改善且仍坚持治疗(平均随访时间 = 18个月;标准差,10.2)。在无人值守的情况下引入NCPAP时未遇到严重并发症。我们能够在完全门诊的环境中对这些患者进行诊断和治疗。