Fanning T G, Seuánez H N, Forman L
Department of Cellular Pathology, AFIP, Washington, DC 20306.
Chromosoma. 1993 May;102(5):306-11. doi: 10.1007/BF00661273.
Two satellite DNAs, designated CapA and CapB, were isolated from the neotropical primate, Cebus apella. The satellites exhibit nonoverlapping distributions on C. apella chromosomes. CapA is a major component of interstitial regions of constitutive heterochromatin, a very large block of heterochromatin comprising most of the long arm of chromosome 11, and some telomeres. The CapA monomer has a length of about 1500 bp and appears recently to have undergone an amplification episode in the C. apella genome. CapA-like sequences are probably present in members of the family Cebidae (to which C. apella belongs), but not in members of the family Callitrichidae (marmosets). CapB sequences can be detected at the centromeres of many C. apella chromosomes, and similar sequences are present in all neotropical primates. The 342 bp CapB monomer shares 60%-64% sequence identity with several alpha satellite sequences of human origin. Because of its structure, sequence, and location, it appears that CapB is the New World primate homolog of Old World primate alpha satellite DNA.
从新热带灵长类动物白喉卷尾猴（Cebus apella）中分离出了两种卫星DNA，分别命名为CapA和CapB。这些卫星DNA在白喉卷尾猴染色体上呈现不重叠分布。CapA是组成型异染色质间隙区域的主要成分，组成型异染色质是一个非常大的异染色质块，包含第11号染色体长臂的大部分以及一些端粒。CapA单体长度约为1500 bp，最近似乎在白喉卷尾猴基因组中经历了一次扩增事件。CapA样序列可能存在于白喉卷尾猴所属的卷尾猴科成员中，但在狨科（狨猴）成员中不存在。CapB序列可在许多白喉卷尾猴染色体的着丝粒处检测到，并且在所有新热带灵长类动物中都存在类似序列。342 bp的CapB单体与几种人类来源的α卫星序列具有60%-64%的序列同一性。由于其结构、序列和位置，CapB似乎是旧世界灵长类动物α卫星DNA在新世界灵长类动物中的同源物。
