丝裂原活化蛋白激酶信号转导通路。 - Suppr

Suppr

超能文献

The mitogen-activated protein kinase signal transduction pathway.

作者信息

Davis R J

机构信息

Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester 01605.

出版信息

J Biol Chem. 1993 Jul 15;268(20):14553-6.

PMID:8325833

Abstract

摘要

相似文献

The mitogen-activated protein kinase signal transduction pathway.丝裂原活化蛋白激酶信号转导通路。

J Biol Chem. 1993 Jul 15;268(20):14553-6.

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.由MEK和MKK亚型定义的独立人类丝裂原活化蛋白激酶信号转导途径。

Science. 1995 Feb 3;267(5198):682-5. doi: 10.1126/science.7839144.

A novel upstream activator in the mitogen-activated protein kinase signal transduction pathway.

Recent Prog Horm Res. 1994;49:341-5. doi: 10.1016/b978-0-12-571149-4.50022-2.

Structural analysis of the MAP kinase ERK2 and studies of MAP kinase regulatory pathways.

Adv Pharmacol. 1996;36:49-65. doi: 10.1016/s1054-3589(08)60576-1.

Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.白细胞介素-2对信号转导及转录激活因子5（STAT5）的激活需要酪氨酸激酶以及一条不同于Raf1/细胞外信号调节激酶2（ERK2）丝裂原活化蛋白激酶（MAPK）途径的丝氨酸/苏氨酸激酶途径的协同作用。

EMBO J. 1996 Apr 15;15(8):1902-13.

Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr protein phosphatase.有丝分裂原诱导的苏氨酸/酪氨酸蛋白磷酸酶使丝裂原活化蛋白激酶去磷酸化并失活。

J Biol Chem. 1993 Aug 5;268(22):16116-9.

Diverse signaling pathways rendezvous at mitogen-activated protein kinase.多种信号通路汇聚于丝裂原活化蛋白激酶。

Exp Hematol. 1993 Oct;21(11):1403-4.

Parallel signal processing among mammalian MAPKs.哺乳动物丝裂原活化蛋白激酶之间的并行信号处理。

Trends Biochem Sci. 1995 Mar;20(3):117-22. doi: 10.1016/s0968-0004(00)88978-1.

Identification of 2 serine residues of MEK-1 that are differentially phosphorylated during activation by raf and MEK kinase.鉴定MEK-1的2个丝氨酸残基，它们在被raf和MEK激酶激活过程中发生差异磷酸化。

J Biol Chem. 1994 Jul 22;269(29):19067-73.

A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody.一种利用磷酸化位点特异性抗体分离底物特异性激酶的新表达克隆策略。

J Immunol Methods. 2001 Jan 1;247(1-2):141-51. doi: 10.1016/s0022-1759(00)00313-6.

引用本文的文献

The edible ethanol extract of suppresses colon cancer progression by inhibiting the proliferation-cell signaling-metastasis axis.[提取物名称]的可食用乙醇提取物通过抑制增殖-细胞信号传导-转移轴来抑制结肠癌进展。

Nutr Res Pract. 2025 Feb;19(1):14-29. doi: 10.4162/nrp.2025.19.1.14. Epub 2024 Oct 2.

Unveiling the Complexities: Exploring Mechanisms of Anthracyclineinduced Cardiotoxicity.揭示复杂性：探索蒽环类药物诱导心脏毒性的机制

Curr Cardiol Rev. 2025;21(2):42-77. doi: 10.2174/011573403X322928241021100631.

Association analysis of polymorphisms in , , , and genes with reproductive traits in different sheep breeds.不同绵羊品种中、、、和基因多态性与繁殖性状的关联分析。

Front Genet. 2024 Apr 12;15:1371872. doi: 10.3389/fgene.2024.1371872. eCollection 2024.

Study of alloferon, a novel immunomodulatory antimicrobial peptide (AMP), and its analogues.新型免疫调节抗菌肽（AMP）阿洛干扰素及其类似物的研究。

Front Pharmacol. 2024 Feb 16;15:1359261. doi: 10.3389/fphar.2024.1359261. eCollection 2024.

Molecular mechanism of the anti-inflammatory and skin protective effects of in human skin keratinocytes.[具体物质]在人皮肤角质形成细胞中的抗炎及皮肤保护作用的分子机制

Food Sci Biotechnol. 2023 Sep 19;33(3):689-697. doi: 10.1007/s10068-023-01380-4. eCollection 2024 Feb.

Mutation in the Common Docking Domain Affects MAP Kinase ERK2 Catalysis and Stability.常见对接结构域中的突变影响丝裂原活化蛋白激酶ERK2的催化作用和稳定性。

Cancers (Basel). 2023 May 26;15(11):2938. doi: 10.3390/cancers15112938.

Identification of BRAF, CCND1, and MYC mutations in a patient with multiple primary malignant tumors: a case report and review of the literature.患者存在多种原发性恶性肿瘤：病例报告及文献复习

World J Surg Oncol. 2023 May 24;21(1):158. doi: 10.1186/s12957-023-03036-3.

Design of an Herbal Preparation Composed by a Combination of L. and L. Extracts, Magnolol and Diosmetin to Address Chronic Venous Diseases through an Anti-Inflammatory Effect and AP-1 Modulation.一种由罗勒提取物和光果甘草提取物、厚朴酚与香叶木素组合而成的草药制剂的设计，旨在通过抗炎作用和AP-1调节来治疗慢性静脉疾病。

Plants (Basel). 2023 Feb 26;12(5):1051. doi: 10.3390/plants12051051.

Phosphorylation of the smooth muscle master splicing regulator RBPMS regulates its splicing activity.磷酸化平滑肌主剪接调控因子 RBPMS 调节其剪接活性。

Nucleic Acids Res. 2022 Nov 11;50(20):11895-11915. doi: 10.1093/nar/gkac1048.

Fine-tuning OsCPK18/OsCPK4 activity via genome editing of phosphorylation motif improves rice yield and immunity.通过磷酸化模体的基因组编辑精细调节 OsCPK18/OsCPK4 的活性可提高水稻产量和免疫力。

Plant Biotechnol J. 2022 Dec;20(12):2258-2271. doi: 10.1111/pbi.13905. Epub 2022 Aug 19.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验