Churchill B M, Aliabadi H, Landau E H, McLorie G A, Steckler R E, McKenna P H, Khoury A E
Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
J Urol. 1993 Aug;150(2 Pt 2):716-20. doi: 10.1016/s0022-5347(17)35596-9.
Virtually all segments of the gastrointestinal tract have been used successfully in augmentation cystoplasty. The complications inherent in enterocystoplasty are well described. Megaureters subtending effete kidneys (poorly or nonfunctioning) provide a novel and excellent source of augmentation material with urothelium and muscular backing, free of the electrolyte and acid base disturbances, and mucus production that plague enterocystoplasty. Augmentation cystoplasty using detubularized, reconfigured, otherwise disposable megaureter, with or without ipsilateral total or partial nephrectomy, was performed in 16 patients (mean age 8.8 years, range 1 to 25) with inadequate and dysfunctional bladders. Postoperative followup varied between 8 and 38 months (mean 22). The overall renal function and radiographic appearance of the remaining upper tracts have remained stable or improved in all patients. Of the 16 patients 15 require intermittent catheterization and 1 voids spontaneously. Ten patients are continent day and night, 5 have improved continence (4 damp at night and 1 stress incontinence) and 1 has failed to gain continence despite good capacity and compliance. Complete postoperative urodynamic evaluations in 12 of 13 patients show good capacity, low pressure bladders with no instability. Complications occurred in 5 patients, including transient urine extravasation in 2, contralateral ureterovesical obstruction in 2 and Mitrofanoff stomal stenosis in 1. Augmentation ureterocystoplasty combines the benefits common to all enterocystoplasties without adding any of the untoward complications or risks associated with nonurothelial augmentations.
几乎胃肠道的所有节段都已成功用于膀胱扩大术。肠膀胱扩大术固有的并发症已有详细描述。伴有无功能或功能不佳肾脏的巨大输尿管提供了一种新颖且优质的扩大材料来源,其带有尿路上皮和肌肉层,没有困扰肠膀胱扩大术的电解质和酸碱平衡紊乱以及黏液分泌问题。对16例膀胱容量不足且功能不良的患者(平均年龄8.8岁,范围1至25岁)实施了膀胱扩大术,术中使用了去管状化、重新构建、否则就废弃的巨大输尿管,同时或不同时进行同侧全肾或部分肾切除术。术后随访时间为8至38个月(平均22个月)。所有患者剩余上尿路的总体肾功能和影像学表现保持稳定或有所改善。16例患者中,15例需要间歇性导尿,1例可自主排尿。10例患者日夜均能保持干爽,5例患者的控尿能力有所改善(4例夜间潮湿,1例压力性尿失禁),1例尽管膀胱容量良好且顺应性佳,但控尿能力仍未改善。13例患者中有12例进行了完整的术后尿动力学评估,结果显示膀胱容量良好、压力低且无不稳定情况。5例患者出现了并发症,包括2例短暂性尿液外渗、2例对侧输尿管膀胱梗阻和1例Mitrofanoff造口狭窄。输尿管膀胱扩大术兼具所有肠膀胱扩大术的优点,且未增加与非尿路上皮扩大相关的任何不良并发症或风险。