De Coene B, Hajnal J V, Pennock J M, Bydder G M
Robert Steiner Magnetic Resonance Unit, Department of Diagnostic Radiology, Hammersmith Hospital, London, UK.
Neuroradiology. 1993;35(5):327-31. doi: 10.1007/BF00588360.
Heavily T2-weighted fluid-attenuated inversion recovery (FLAIR) sequences with inversion times of 2000-2500 ms and echo times of 130-200 ms were used to image the brain stem of a normal adult and five patients. These sequences produce high signal from many white matter tracts and display high lesion contrast. The corticospinal and parietopontine tracts, lateral and medial lemnisci, superior and inferior cerebellar peduncles, medial longitudinal fasciculi, thalamo-olivary tracts and the cuneate and gracile fasciculi gave high signal and were directly visualised. The oculomotor and trigeminal nerves were demonstrated within the brain stem. Lesions not seen with conventional T2-weighted spin echo sequences were seen with high contrast in patients with infarction, multiple sclerosis, sarcoidosis, shunt obstruction and metastatic tumour. The anatomical detail and high lesion contrast given by the FLAIR pulse sequence appear likely to be of value in diagnosis of disease in the brain stem.
采用反转时间为2000 - 2500毫秒、回波时间为130 - 200毫秒的重T2加权液体衰减反转恢复（FLAIR）序列，对一名正常成年人及五名患者的脑干进行成像。这些序列在许多白质束中产生高信号，并显示出高病变对比度。皮质脊髓束和顶桥束、外侧和内侧丘系、上、下小脑脚、内侧纵束、丘脑橄榄束以及楔束和薄束发出高信号并可直接显示。动眼神经和三叉神经在脑干部位得以显示。在患有梗死、多发性硬化、结节病、分流梗阻和转移性肿瘤的患者中，常规T2加权自旋回波序列未发现的病变在FLAIR序列中以高对比度显示出来。FLAIR脉冲序列所提供的解剖细节和高病变对比度似乎对脑干疾病的诊断具有重要价值。
