Zuskin E, Butkovic D, Schachter E N, Mustajbegovic J
Andrija Stampar School of Public Health, Zagreb. Croatia.
Am J Ind Med. 1993 Jun;23(6):835-44. doi: 10.1002/ajim.4700230602.
A group of 80 men employed in the glassblowing industry was studied in order to investigate the effect of this occupational exposure on respiratory function. Eighty nonexposed workers were included in the study as a control group. Glassblowers had a significantly higher prevalence of chronic bronchitis, nasal catarrh, chronic sinusitis, and nasal bleeding than control workers; length of employment in the industry did not affect the prevalence of symptoms. Many of the glassblowers complained of work shift related symptoms. Measurement of lung function among glassblowers showed there were significant increases in the forced vital capacity (FVC) and the maximum flow rates at 50% and 25% of FVC on maximum expiratory flow volume (MEFV) curves (FEF50, FEF25) across the work shift. Glassblowers had significantly larger preshift FVC and forced expiratory volume in 1-second (FEV1) measurements when compared to controls. Additionally, residual volume (RV) and RV/TLC% for the glassblowers were significantly increased while the diffusing capacity (DLCO) was normal (when compared to predicted values). Our data indicate that employment in the glassblowing industry contributes to the development of chronic respiratory findings.
为了研究这种职业暴露对呼吸功能的影响，对一组80名从事吹玻璃行业的男性进行了研究。80名未暴露的工人作为对照组纳入研究。吹玻璃工人患慢性支气管炎、鼻粘膜炎、慢性鼻窦炎和鼻出血的患病率明显高于对照工人；在该行业的工作年限并不影响症状的患病率。许多吹玻璃工人抱怨有与轮班相关的症状。对吹玻璃工人的肺功能测量显示，在整个轮班期间，用力肺活量（FVC）以及最大呼气流量容积（MEFV）曲线中FVC的50%和25%处的最大流速（FEF50、FEF25）显著增加。与对照组相比，吹玻璃工人班前FVC和一秒用力呼气量（FEV1）测量值明显更大。此外，吹玻璃工人的残气量（RV）和RV/TLC%显著增加，而弥散量（DLCO）正常（与预测值相比）。我们的数据表明，从事吹玻璃行业会导致慢性呼吸系统疾病的发生。
