化脓性链球菌产生的新型羊毛硫抗生素A-FF22编码基因的克隆及其核苷酸序列测定。
Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence.
作者信息
Hynes W L, Ferretti J J, Tagg J R
机构信息
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190.
出版信息
Appl Environ Microbiol. 1993 Jun;59(6):1969-71. doi: 10.1128/aem.59.6.1969-1971.1993.
Abstract
Streptococcin A-FF22 (SA-FF22) is a lantibiotic produced by Streptococcus pyogenes FF22. The nucleotide sequence of the SA-FF22 structural gene (scnA) was determined and shown to encode a 51-amino-acid prepeptide. The proteolytic processing site of the SA-FF22 prepeptide differs from that which characterizes other type A lantibiotics.
摘要
链球菌素A-FF22（SA-FF22）是化脓性链球菌FF22产生的一种羊毛硫抗生素。已确定SA-FF22结构基因（scnA）的核苷酸序列，并显示其编码一个含51个氨基酸的前肽。SA-FF22前肽的蛋白水解加工位点与其他A型羊毛硫抗生素的特征位点不同。
Zotero 插件