Katz J D, Senecal J L, Rivest C, Goulet J R, Rothfield N
Department of Medicine, University of Connecticut School of Medicine, Farmington 06030.
Lupus. 1993 Apr;2(2):119-23. doi: 10.1177/096120339300200210.
Although indices of activity for systemic lupus erythematosus have been developed and validated, a disease staging system requires the measurement of severity as well. We have constructed such a scale, the Lupus Severity of Disease Index (Lupus SDI). Accepted clinical, pathologic and physiologic classification schemes were employed to validate this index at two separate research institutions. The Lupus SDI allows homogenization of patient populations for the purposes of research and, possibly, for case mix adjustment.
尽管系统性红斑狼疮的活动指数已经得到开发和验证，但疾病分期系统同样需要对严重程度进行衡量。我们构建了这样一个量表，即狼疮疾病严重程度指数（Lupus SDI）。在两个不同的研究机构采用公认的临床、病理和生理分类方案对该指数进行验证。Lupus SDI能够使患者群体同质化，以用于研究目的，也可能用于病例组合调整。
