Williams S, Gooch C, Cockcroft A
Occupational Health Unit, Royal Free Hospital and School of Medicine, Hampstead, London, UK.
Br J Surg. 1993 Jun;80(6):714-6. doi: 10.1002/bjs.1800800611.
A questionnaire was sent to all 158 staff of the operating department of a London teaching hospital to confirm their hepatitis B immunization status and establish the number of incidents involving exposure to blood during the preceding 4 weeks. Of these personnel, 104 (66 per cent) were known to be immune to hepatitis B either through immunization (97) or previous infection (seven). A further 23 (15 per cent) had completed a course of immunization but their seroconversion had not been checked. There were 26 sharps injuries sustained by 14 (12 per cent) of 119 staff and 240 other exposures to blood. Four of the sharps injuries had been reported. Staff known to be immune were more likely than those with unknown or negative immunity to report incidents (20 versus 0 per cent (95 per cent confidence interval of difference 2-38 per cent)). Doctors sustained more non-sharps exposures to blood than others (47 versus 23 per cent (95 per cent confidence interval of difference 7-40 per cent)). An important minority of operating department staff remains unimmunized against hepatitis B, although exposure to blood is common. Incidents are rarely reported and staff with unknown or negative immunity seem less likely to report than those known to be immune.
一份调查问卷被发送给伦敦一家教学医院手术室的所有158名工作人员，以确认他们的乙肝免疫状况，并确定在过去4周内涉及血液暴露的事件数量。在这些人员中，已知104人（66%）通过免疫接种（97人）或既往感染（7人）对乙肝具有免疫力。另有23人（15%）完成了免疫接种疗程，但未检查其血清转化情况。119名工作人员中有14人（12%）发生了26起锐器伤，另有240次其他血液暴露。其中4起锐器伤已上报。已知具有免疫力的工作人员比免疫情况未知或免疫阴性的工作人员更有可能上报事件（分别为20%和0%（差异的95%置信区间为2%-38%））。医生发生的非锐器血液暴露比其他人员更多（分别为47%和23%（差异的95%置信区间为7%-40%））。尽管血液暴露很常见，但手术室工作人员中仍有相当一部分人未接种乙肝疫苗。事件很少被上报，免疫情况未知或免疫阴性的工作人员似乎比已知具有免疫力的工作人员更不愿意上报。
