生长激素治疗的间歇性给药与持续性给药
Intermittent versus continuous administration of growth hormone treatment.
作者信息
Hakeem V, Hindmarsh P C, Brook C G
机构信息
Endocrine Unit, Middlesex Hospital, London.
出版信息
Arch Dis Child. 1993 Jun;68(6):783-4. doi: 10.1136/adc.68.6.783.
Abstract
Growth hormone treatment given by daily injection was compared with growth hormone given for three weeks of every four. All children had received recombinant human growth hormone for two years before randomisation. Growth velocity decreased in both groups in years one and two of the study but the effect was significantly greater in the group receiving intermittent growth hormone.
摘要
将每日注射生长激素的治疗方法与每四周中有三周注射生长激素的方法进行了比较。所有儿童在随机分组前均已接受重组人生长激素治疗两年。在研究的第一年和第二年，两组儿童的生长速度均有所下降，但接受间歇性生长激素治疗的组下降幅度明显更大。
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