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人工流产对后续生育能力的影响。

The effect of induced abortion on subsequent fertility.

作者信息

Frank P, McNamee R, Hannaford P C, Kay C R, Hirsch S

机构信息

Royal College of General Practitioners, Manchester, UK.

出版信息

Br J Obstet Gynaecol. 1993 Jun;100(6):575-80. doi: 10.1111/j.1471-0528.1993.tb15313.x.

Abstract

OBJECTIVE

To investigate the effect of induced abortion on subsequent fertility.

DESIGN

  1. Prospective cohort study of women who had an unplanned pregnancy at recruitment. 2. Retrospective study of women who had a planned pregnancy at recruitment.

SETTING

Joint Royal College of General Practitioners/Royal College of Obstetricians and Gynaecologists study based in general practice in England, Scotland and Wales, between 1976 and 1987.

SUBJECTS

  1. Prospective study: Four hundred and thirty-three women with a recruitment unplanned pregnancy ending in induced abortion (abortion group) and 1035 women with a recruitment unplanned pregnancy which ended naturally (nonabortion group). All subsequently had a planned pregnancy, or were known to be trying to conceive at some point during the follow-up. 2. Retrospective study: Nine thousand two hundred and ninety-nine women who presented at recruitment with a planned pregnancy.

MAIN OUTCOME MEASURE

The women's estimated length of planning time, expressed as a fertility rate ratio.

RESULTS

Induced abortion was not related to future fertility. In the prospective study, the fertility rate ratio (FRR) of the abortion group relative to the nonabortion group was 0.94 (95% CI 0.83 to 1.07, P = 0.37). This result was supported by the retrospective study, which again showed no important difference between the two groups.

CONCLUSION

Induced abortion does not appear to have an important effect on future fertility.

摘要

目的

探讨人工流产对后续生育能力的影响。

设计

  1. 对招募时意外怀孕女性的前瞻性队列研究。2. 对招募时计划怀孕女性的回顾性研究。

背景

1976年至1987年期间,基于英格兰、苏格兰和威尔士的全科医疗开展的皇家全科医师学院/皇家妇产科学院联合研究。

研究对象

  1. 前瞻性研究:433名招募时意外怀孕并以人工流产告终的女性(流产组)和1035名招募时意外怀孕但自然结束妊娠的女性(非流产组)。所有女性随后均有计划怀孕,或在随访期间的某个时间点已知正在尝试受孕。2. 回顾性研究:9299名招募时计划怀孕的女性。

主要观察指标

以生育率比表示的女性估计计划怀孕时间长度。

结果

人工流产与未来生育能力无关。在前瞻性研究中,流产组相对于非流产组的生育率比(FRR)为0.94(95%可信区间0.83至1.07,P = 0.37)。回顾性研究支持了这一结果,该研究再次表明两组之间无显著差异。

结论

人工流产似乎对未来生育能力没有重要影响。

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