Mahomed K, James D, Golding J, McCabe R
University Department of Obstetrics and Gynaecology, Avondale, Harare, Zimbabwe.
Eur J Obstet Gynecol Reprod Biol. 1993 Mar;48(3):169-75. doi: 10.1016/0028-2243(93)90084-p.
As part of a double-blind randomised controlled trial to test the efficacy of 20 mg of zinc supplementation during pregnancy, 494 mothers were enrolled at booking. After giving informed consent they were asked to taste a dilute solution of zinc sulphate. Of the 489 mothers who were given the solution, 44 (9%) were unable to taste it. Mothers who failed this test did not differ significantly from the rest of the population in background factors such as social class, ethnic group, maternal age or parity. Significantly more non-tasting mothers had had a previous growth-retarded infant. Their diets did not differ in any way from those of the tasters. Zinc supplementation did not affect their taste as assessed at the end of pregnancy. Of the possible outcome measures considered, the zinc taste test did predict whether the mother was to develop diastolic hypertension (23% of non-tasters, 8% of tasters), but the mean birthweight, preterm delivery rate and other outcomes were identical.
作为一项双盲随机对照试验的一部分，该试验旨在测试孕期补充20毫克锌的功效，494名母亲在预约时登记入组。在获得知情同意后，她们被要求品尝硫酸锌的稀释溶液。在489名服用该溶液的母亲中，44名（9%）无法尝出味道。在社会阶层、种族、母亲年龄或产次等背景因素方面，未能通过此项测试的母亲与其他母亲没有显著差异。味觉测试未通过的母亲中，曾生育过发育迟缓婴儿的人数明显更多。她们的饮食与能尝出味道的母亲没有任何差异。孕期结束时评估发现，补充锌并未影响她们的味觉。在所考虑的可能的结果指标中，锌味觉测试确实能够预测母亲是否会患舒张期高血压（味觉测试未通过的母亲中有23%患病，味觉测试通过的母亲中有8%患病），但平均出生体重、早产率和其他结果并无差异。
