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爱尔兰西部腹腔疾病患者和对照人群中的α1-抗胰蛋白酶表型

Alpha 1-antitrypsin phenotypes in coeliac patients and a control population in the west of Ireland.

作者信息

Bourke M, O'Donovan M, Stevens F M, McCarthy C F

机构信息

Department of Medicine, University College Hospital, Galway.

出版信息

Ir J Med Sci. 1993 May;162(5):171-2. doi: 10.1007/BF02945176.

Abstract

alpha 1 antitrypsin or protease inhibitor (Pi) phenotyping was carried out on 111 coeliac disease patients (CD) and 250 controls. The Pi MM phenotype was present in 95 (85.6%) of the coeliacs and 225 (90%) of the controls. The groups did not differ significantly with regard to Pi phenotypes. In the CD group the Pi Phenotype did not relate to HLA B8 or DR3 status. Associated diseases in the CD patients did not correlate with Pi phenotype.

摘要

对111例乳糜泻患者(CD)和250名对照者进行了α1抗胰蛋白酶或蛋白酶抑制剂(Pi)表型分析。乳糜泻患者中有95例(85.6%)表现为Pi MM表型,对照者中有225例(90%)表现为该表型。两组在Pi表型方面无显著差异。在CD组中,Pi表型与HLA B8或DR3状态无关。CD患者的相关疾病与Pi表型无相关性。

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