• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
The tet(K) gene from Staphylococcus aureus mediates the transport of potassium in Escherichia coli.来自金黄色葡萄球菌的tet(K)基因介导了大肠杆菌中钾的转运。
J Bacteriol. 1993 Aug;175(15):4927-9. doi: 10.1128/jb.175.15.4927-4929.1993.
2
The tetracycline efflux protein encoded by the tet(K) gene from Staphylococcus aureus is a metal-tetracycline/H+ antiporter.金黄色葡萄球菌tet(K)基因编码的四环素外排蛋白是一种金属四环素/H⁺反向转运体。
FEBS Lett. 1995 May 29;365(2-3):193-7. doi: 10.1016/0014-5793(95)00455-i.
3
The tet(K) gene of plasmid pT181 of Staphylococcus aureus encodes an efflux protein that contains 14 transmembrane helices.金黄色葡萄球菌质粒pT181的tet(K)基因编码一种含有14个跨膜螺旋的外排蛋白。
Plasmid. 1993 Sep;30(2):163-6. doi: 10.1006/plas.1993.1045.
4
Transmembrane glutamic acid residues play essential roles in the metal-tetracycline/H+ antiporter of Staphylococcus aureus.
FEBS Lett. 1996 Aug 12;391(3):243-6. doi: 10.1016/0014-5793(96)00743-0.
5
Expression in Escherichia coli of a TetK determinant from Staphylococcus aureus.金黄色葡萄球菌TetK决定簇在大肠杆菌中的表达。
Biol Pharm Bull. 1994 Feb;17(2):352-5. doi: 10.1248/bpb.17.352.
6
Detection of tet(K) and tet(M) in Staphylococcus aureus of Asian countries by the polymerase chain reaction.通过聚合酶链反应检测亚洲国家金黄色葡萄球菌中的tet(K)和tet(M)
J Antibiot (Tokyo). 1996 Nov;49(11):1127-32. doi: 10.7164/antibiotics.49.1127.
7
Presence of the Tet M determinant in a clinical isolate of Acinetobacter baumannii.鲍曼不动杆菌临床分离株中四环素抗性决定因子的存在。
Antimicrob Agents Chemother. 2003 Jul;47(7):2310-2. doi: 10.1128/AAC.47.7.2310-2312.2003.
8
Characterization of the tetracycline resistance gene of plasmid pT181 of Staphylococcus aureus.金黄色葡萄球菌质粒pT181四环素抗性基因的特性分析。
J Bacteriol. 1988 Dec;170(12):5522-8. doi: 10.1128/jb.170.12.5522-5528.1988.
9
An N-terminal domain of the tetracycline resistance protein increases susceptibility to aminoglycosides and complements potassium uptake defects in Escherichia coli.四环素抗性蛋白的N端结构域增加了大肠杆菌对氨基糖苷类药物的敏感性并弥补了钾摄取缺陷。
J Bacteriol. 1988 Feb;170(2):598-604. doi: 10.1128/jb.170.2.598-604.1988.
10
Twelve-transmembrane-segment (TMS) version (DeltaTMS VII-VIII) of the 14-TMS Tet(L) antibiotic resistance protein retains monovalent cation transport modes but lacks tetracycline efflux capacity.14个跨膜区段(TMS)的Tet(L)抗生素抗性蛋白的12个跨膜区段版本(DeltaTMS VII-VIII)保留单价阳离子转运模式,但缺乏四环素外排能力。
J Bacteriol. 2001 Apr;183(8):2667-71. doi: 10.1128/JB.183.8.2667-2671.2001.

引用本文的文献

1
Tetracycline Antibiotics and Resistance.四环素类抗生素与耐药性
Cold Spring Harb Perspect Med. 2016 Apr 1;6(4):a025387. doi: 10.1101/cshperspect.a025387.
2
Biochemistry of bacterial multidrug efflux pumps.细菌多药外排泵的生物化学
Int J Mol Sci. 2012;13(4):4484-4495. doi: 10.3390/ijms13044484. Epub 2012 Apr 10.
3
Improvement in K+-limited growth rate associated with expression of the N-terminal fragment of one subunit (KdpA) of the multisubunit Kdp transporter in Escherichia coli.大肠杆菌中多亚基 Kdp 转运蛋白一个亚基(KdpA)的 N 端片段表达与 K⁺ 限制生长速率的提高相关。
J Bacteriol. 2001 Jun;183(11):3515-20. doi: 10.1128/JB.183.11.3515-3520.2001.
4
Twelve-transmembrane-segment (TMS) version (DeltaTMS VII-VIII) of the 14-TMS Tet(L) antibiotic resistance protein retains monovalent cation transport modes but lacks tetracycline efflux capacity.14个跨膜区段(TMS)的Tet(L)抗生素抗性蛋白的12个跨膜区段版本(DeltaTMS VII-VIII)保留单价阳离子转运模式,但缺乏四环素外排能力。
J Bacteriol. 2001 Apr;183(8):2667-71. doi: 10.1128/JB.183.8.2667-2671.2001.
5
The TetA(K) tetracycline/H(+) antiporter from Staphylococcus aureus: mutagenesis and functional analysis of motif C.金黄色葡萄球菌的TetA(K)四环素/H(+)反向转运蛋白:基序C的诱变与功能分析
J Bacteriol. 2000 Mar;182(6):1492-8. doi: 10.1128/JB.182.6.1492-1498.2000.
6
Characterization of cadmium uptake in Lactobacillus plantarum and isolation of cadmium and manganese uptake mutants.植物乳杆菌中镉吸收的特性及镉和锰吸收突变体的分离
Appl Environ Microbiol. 1999 Nov;65(11):4741-5. doi: 10.1128/AEM.65.11.4741-4745.1999.
7
Na+/H+ antiport activity conferred by Bacillus subtilis tetA(L), a 5' truncation product of tetA(L), and related plasmid genes upon Escherichia coli.枯草芽孢杆菌tetA(L)(tetA(L)的5'截短产物)及相关质粒基因赋予大肠杆菌的Na⁺/H⁺逆向转运活性。
Antimicrob Agents Chemother. 1996 Apr;40(4):852-7. doi: 10.1128/AAC.40.4.852.
8
Chromosomal tetA(L) gene of Bacillus subtilis: regulation of expression and physiology of a tetA(L) deletion strain.枯草芽孢杆菌的染色体tetA(L)基因:tetA(L)缺失菌株的表达调控与生理学研究
J Bacteriol. 1996 May;178(10):2853-60. doi: 10.1128/jb.178.10.2853-2860.1996.

本文引用的文献

1
Expression of the tetK gene from Staphylococcus aureus in Escherichia coli: comparison of substrate specificities of TetA(B), TetA(C), and TetK efflux proteins.金黄色葡萄球菌tetK基因在大肠杆菌中的表达:TetA(B)、TetA(C)和TetK外排蛋白底物特异性的比较。
Antimicrob Agents Chemother. 1993 Feb;37(2):191-8. doi: 10.1128/AAC.37.2.191.
2
Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.大肠杆菌中由四种基因不同的四环素抗性决定簇编码的四环素主动外排
Proc Natl Acad Sci U S A. 1980 Jul;77(7):3974-7. doi: 10.1073/pnas.77.7.3974.
3
Tetracycline resistance element of pBR322 mediates potassium transport.pBR322的四环素抗性元件介导钾离子转运。
J Bacteriol. 1984 Dec;160(3):1188-90. doi: 10.1128/jb.160.3.1188-1190.1984.
4
Detection of an inducible membrane protein associated with R-factor-mediated tetracycline resistance.与R因子介导的四环素抗性相关的一种可诱导膜蛋白的检测。
Biochem Biophys Res Commun. 1974 Feb 27;56(4):1060-8. doi: 10.1016/s0006-291x(74)80296-2.
5
Energetics of tetracycline efflux system encoded by Tn10 in Escherichia coli.大肠杆菌中Tn10编码的四环素外排系统的能量学
FEBS Lett. 1985 Dec 2;193(2):194-8. doi: 10.1016/0014-5793(85)80149-6.
6
Energy-dependent efflux mediated by class L (tetL) tetracycline resistance determinant from streptococci.由链球菌的L类(tetL)四环素抗性决定簇介导的能量依赖性外排。
Antimicrob Agents Chemother. 1987 Oct;31(10):1648-50. doi: 10.1128/AAC.31.10.1648.
7
An N-terminal domain of the tetracycline resistance protein increases susceptibility to aminoglycosides and complements potassium uptake defects in Escherichia coli.四环素抗性蛋白的N端结构域增加了大肠杆菌对氨基糖苷类药物的敏感性并弥补了钾摄取缺陷。
J Bacteriol. 1988 Feb;170(2):598-604. doi: 10.1128/jb.170.2.598-604.1988.
8
The proton motive force in bacteria: a critical assessment of methods.细菌中的质子动力势:方法的批判性评估
Annu Rev Microbiol. 1985;39:219-42. doi: 10.1146/annurev.mi.39.100185.001251.
9
Topology of the transposon Tn10-encoded tetracycline resistance protein within the inner membrane of Escherichia coli.转座子Tn10编码的四环素抗性蛋白在大肠杆菌内膜中的拓扑结构。
J Biol Chem. 1989 Jul 15;264(20):11663-70.
10
Proton-linked sugar transport systems in bacteria.细菌中的质子偶联糖转运系统。
J Bioenerg Biomembr. 1990 Aug;22(4):525-69. doi: 10.1007/BF00762961.

来自金黄色葡萄球菌的tet(K)基因介导了大肠杆菌中钾的转运。

The tet(K) gene from Staphylococcus aureus mediates the transport of potassium in Escherichia coli.

作者信息

Guay G G, Tuckman M, McNicholas P, Rothstein D M

机构信息

Department of Microbial Genetics and Biochemistry, Lederle Laboratories, Pearl River, New York 10965.

出版信息

J Bacteriol. 1993 Aug;175(15):4927-9. doi: 10.1128/jb.175.15.4927-4929.1993.

DOI:10.1128/jb.175.15.4927-4929.1993
PMID:8335648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC204949/
Abstract

The tet(K) gene, encoding the tetracycline efflux protein from Staphylococcus aureus, mediates the transport of potassium in an Escherichia coli mutant defective in potassium uptake. Deletion mapping indicates that the first third of the tet(K) gene is sufficient to mediate potassium transport.

摘要

编码来自金黄色葡萄球菌的四环素外排蛋白的tet(K)基因,在一个钾摄取存在缺陷的大肠杆菌突变体中介导钾的转运。缺失作图表明tet(K)基因的前三分之一足以介导钾的转运。