金黄色葡萄球菌质粒pT181的tet(K)基因编码一种含有14个跨膜螺旋的外排蛋白。
The tet(K) gene of plasmid pT181 of Staphylococcus aureus encodes an efflux protein that contains 14 transmembrane helices.
作者信息
Guay G G, Khan S A, Rothstein D M
机构信息
Department of Microbial Genetics, Lederle Laboratories, Pearl River, New York 10965.
出版信息
Plasmid. 1993 Sep;30(2):163-6. doi: 10.1006/plas.1993.1045.
PMID:8234490
Abstract
The corrected DNA sequence of the tet(K) structural gene, encoding the tetracycline efflux protein from Staphylococcus aureus, is reported. The Tet(K) protein is homologous to related tetracycline efflux proteins throughout the protein, including at the C-terminal end. Hydropathy plotting now clearly indicates that the Tet(K) protein contains 14 transmembrane alpha-helices.
摘要
报道了编码金黄色葡萄球菌四环素外排蛋白的tet(K)结构基因的校正DNA序列。Tet(K)蛋白在整个蛋白质中，包括在C末端，与相关的四环素外排蛋白同源。亲水性图谱现在清楚地表明，Tet(K)蛋白含有14个跨膜α螺旋。
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