Nagata Y, Fujino Y, Matsumoto S, Mochizuki M, Oka S, Kimura S, Shimada K, Wakabayashi T
Eye Clinic, Self Defense Forces Central Hospital, Setagaya-ku, Japan.
Nippon Ganka Gakkai Zasshi. 1993 May;97(5):655-60.
A case of cryptococcal retinochoroiditis associated with acquired immunodeficiency syndrome (AIDS) is reported. The patient was a 22-year-old man with hemophilia A. He was found seropositive for human immunodeficiency virus three years ago. He was admitted with complaints of fever and cough. CD4/CD8 ratio was 0.01 and CD4 lymphocyte count was 10/mm3. Two weeks later, ophthalmological examination revealed some yellowish white focal lesions at the posterior fundus. More detailed examinations were impossible because of his poor general condition. He died one month later. The autopsy showed disseminated cryptococcosis. Ocular histopathological examination revealed cryptococcal retinochoroiditis without any inflammatory reaction. This is the first report in Japan of this disease associated with AIDS and of a histopathological study of it.
报告了一例与获得性免疫缺陷综合征（艾滋病）相关的隐球菌性视网膜脉络膜炎病例。患者为一名22岁的甲型血友病男性。三年前他被检测出人类免疫缺陷病毒血清阳性。他因发热和咳嗽入院。CD4/CD8比值为0.01，CD4淋巴细胞计数为10/mm³。两周后，眼科检查发现眼底后部有一些黄白色局灶性病变。由于他的全身状况较差，无法进行更详细的检查。一个月后他去世。尸检显示播散性隐球菌病。眼部组织病理学检查显示隐球菌性视网膜脉络膜炎，无任何炎症反应。这是日本首例关于这种与艾滋病相关疾病及其组织病理学研究的报告。
