Kopans D B
Department of Radiology, Massachusetts General Hospital, Boston 02114.
Cancer. 1993 Aug 15;72(4 Suppl):1457-60. doi: 10.1002/1097-0142(19930815)72:4+<1457::aid-cncr2820721407>3.0.co;2-e.
The poor results of the National Breast Screening Study of Canada regarding the screening of women aged 40-49 have been interpreted to suggest that mammography might be detrimental. Our comparison of women who had mammography and had their cancers detected by mammography with women who did not have mammography and had palpable cancers suggest that this is not the case. There is no detrimental effect; rather, the use of mammography results in an improvement in survival. The poor results of the National Breast Screening Study likely are due to the unbalanced allocation of women with advanced cancers to the screened group, the poor quality of the mammography in the trial, and an insufficient sample size.
加拿大全国乳腺筛查研究针对40至49岁女性进行筛查的结果不佳，这被解读为意味着乳房X光检查可能有害。我们将进行了乳房X光检查且通过该检查发现癌症的女性与未进行乳房X光检查但有可触及肿块的癌症患者进行比较，结果表明情况并非如此。乳房X光检查没有有害影响；相反，使用乳房X光检查能提高生存率。加拿大全国乳腺筛查研究结果不佳可能是由于患有晚期癌症的女性在筛查组中的分配不均衡、试验中乳房X光检查质量差以及样本量不足。
