Esayag-Tendler B, White W B
Department of Medicine, University of Connecticut School of Medicine, Farmington.
Cleve Clin J Med. 1993 Jul-Aug;60(4):278-83. doi: 10.3949/ccjm.60.4.278.
The first fully automatic portable invasive blood pressure recorder was developed 30 years ago. Today, portable noninvasive ambulatory blood pressure devices are capable of measuring blood pressure intermittently for periods of 24 to 48 hours.
To discuss the utility of automatic ambulatory blood pressure recording in assessing antihypertensive therapy.
Ambulatory blood pressure monitoring is helpful in assessing the pharmacodynamics and the clinical efficacy of antihypertensive drugs. It is superior to office blood pressure measurement in predicting hypertensive end-organ disease. In clinical trials, ambulatory blood pressure monitoring permits a more varied population to enter a study, the number of subjects required is often reduced, and a placebo control group may be unnecessary.
The various methods of analyzing ambulatory blood pressure data should be used in a complementary fashion to evaluate antihypertensive drug therapy. We believe that this technique will soon become much more commonly used for hypertension management.
30年前研发出了第一台全自动便携式有创血压记录仪。如今,便携式无创动态血压设备能够间歇性测量血压达24至48小时。
探讨自动动态血压记录在评估降压治疗中的作用。
动态血压监测有助于评估降压药物的药效学及临床疗效。在预测高血压靶器官疾病方面,它优于诊室血压测量。在临床试验中,动态血压监测允许更多样化的人群进入研究,所需受试者数量常常减少,且可能无需安慰剂对照组。
应采用多种分析动态血压数据的方法相互补充,以评估降压药物治疗。我们认为,这项技术很快将在高血压管理中得到更广泛的应用。