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Localisation of the human nuclear factor I/X (NFI/X) gene to chromosome 19p13 and detection of five other related loci at 1p21-22, 1q42-43, 5q15, 11p13 and 20q13 by FISH.

作者信息

Seisenberger C, Winnacker E L, Scherthan H

机构信息

Institut für Biochemie, MPI für Biochemie, Martinsried, Germany.

出版信息

Hum Genet. 1993 Jul;91(6):535-7. doi: 10.1007/BF00205076.

DOI:10.1007/BF00205076
PMID:8340106
Abstract

Nuclear factor I (NFI) is a member of a family of dimeric DNA-binding proteins that are involved both in the initiation of adenovirus DNA replication and in the stimulation of transcriptional activation. We have used fluorescence in situ hybridisation (FISH) to map one of four known genes encoding an NFI protein, the human NFI/X gene, to chromosome 19p1.3. Secondary sites of hybridisation observed at 5p1.5, 1q4.2-4.4, 1p2.1-2.2, and 20p1.3 most likely are attributable to partial sequence homologies with related NFI genes.

摘要

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Localisation of the human nuclear factor I/X (NFI/X) gene to chromosome 19p13 and detection of five other related loci at 1p21-22, 1q42-43, 5q15, 11p13 and 20q13 by FISH.
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2
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本文引用的文献

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The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded linear DNA.TGGCA结合蛋白：一种识别双链线性DNA上对称序列的真核细胞核蛋白。
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一种核因子I/X（）基因发生移码突变的小鼠模型具有马歇尔-史密斯综合征的表型特征。
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Assignment of the porcine nuclear factor I/CTF (NFI/CTF) gene to chromosome 2q12-13 by FISH.通过荧光原位杂交将猪核因子I/CTF（NFI/CTF）基因定位到2号染色体q12-13区域。
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5
A quantitative analysis of nuclear factor I/DNA interactions.核因子I与DNA相互作用的定量分析。
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6
Purification methods for the sequence-specific DNA-binding protein nuclear factor I (NFI)--generation of protein sequence information.序列特异性DNA结合蛋白核因子I（NFI）的纯化方法——蛋白质序列信息的生成
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7
Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.多个基因编码与3-羟基-3-甲基戊二酰辅酶A还原酶启动子结合的核因子1样蛋白。
Proc Natl Acad Sci U S A. 1988 Dec;85(23):8963-7. doi: 10.1073/pnas.85.23.8963.
8
Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA.从大鼠肝脏中纯化一种类神经纤维瘤蛋白1（NF1）的DNA结合蛋白并克隆相应的cDNA。
EMBO J. 1988 Oct;7(10):3115-23. doi: 10.1002/j.1460-2075.1988.tb03178.x.
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Chicken NFI/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes.鸡的NFI/TGGCA蛋白由至少三个独立基因编码：NFI-A、NFI-B和NFI-C，在哺乳动物基因组中有同源物。
Nucleic Acids Res. 1990 May 11;18(9):2607-16. doi: 10.1093/nar/18.9.2607.
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High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones.利用黏粒克隆原位杂交对人类11号染色体进行高分辨率图谱绘制。
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