Bell G D, Powell K U
Dept. of Medicine, Ipswich Hospital, UK.
Scand J Gastroenterol Suppl. 1993;196:7-11. doi: 10.3109/00365529309098334.
Since Helicobacter pylori was first cultured 10 years ago, there have been remarkable changes in our approach to the therapy of peptic ulcer disease. We now know that 90% of duodenal ulcer patients and 70% of all gastric ulcer patients are infected with H. pylori. Evidence is presented that the relapse rate of both duodenal and gastric ulcers can be substantially reduced if the bacterium is eradicated from the patient's stomach. Some of the anti-H. pylori eradication regimens currently available are discussed, with particular emphasis on the relative merits of standard triple therapy and an omeprazole/amoxycillin combination.
自从10年前首次培养出幽门螺杆菌以来，我们治疗消化性溃疡疾病的方法已发生了显著变化。我们现在知道，90%的十二指肠溃疡患者和70%的胃溃疡患者感染了幽门螺杆菌。有证据表明，如果从患者胃部根除这种细菌，十二指肠溃疡和胃溃疡的复发率均可大幅降低。本文讨论了目前可用的一些根除幽门螺杆菌的治疗方案，特别强调了标准三联疗法和奥美拉唑/阿莫西林联合疗法的相对优点。
