Lambert K G, Kinsley C H
Department of Psychology, Randolph-Macon College, Ashland, VA 23005.
Physiol Behav. 1993 Jun;53(6):1085-90. doi: 10.1016/0031-9384(93)90363-k.
The present study investigated the effect of gonadal hormones on activity, food consumption, severity of ulceration, weight loss, and survival duration in male and female rats exposed to the activity-stress (A-S) paradigm. Animals received either sham surgery or gonadectomy and were housed in activity wheels or standard suspended cages. Results indicated that gonadectomized animals were more likely to engage in high running levels in the A-S paradigm; in addition, castrated males developed significantly more ulceration than the other groups. Neither sex nor gonadectomy affected the survival duration of A-S animals.
本研究调查了性腺激素对暴露于活动应激（A-S）范式下的雄性和雌性大鼠的活动、食物消耗、溃疡严重程度、体重减轻及存活时间的影响。动物接受假手术或性腺切除术，并饲养在活动轮或标准悬挂笼中。结果表明，性腺切除的动物在A-S范式下更有可能进行高强度跑步；此外，去势雄性大鼠的溃疡发展程度明显高于其他组。性别和性腺切除术均未影响A-S动物的存活时间。
