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合成代谢类固醇和生长激素。

Anabolic steroids and growth hormone.

作者信息

Haupt H A

机构信息

Orthopaedic Associates, Inc., Missouri Baptist Hospital, Diagnostic Center, St. Louis 63131.

出版信息

Am J Sports Med. 1993 May-Jun;21(3):468-74. doi: 10.1177/036354659302100324.

Abstract

Athletes are generally well educated regarding substances that they may use as ergogenic aids. This includes anabolic steroids and growth hormone. Fortunately, the abuse of growth hormone is limited by its cost and the fact that anabolic steroids are simply more enticing to the athlete. There are, however, significant potential adverse effects regarding its use that can be best understood by studying known growth hormone excess, as demonstrated in the acromegalic syndrome. Many athletes are unfamiliar with this syndrome and education of the potential consequences of growth hormone excess is important in counseling athletes considering its use. While athletes contemplating the use of anabolic steroids may correctly perceive their risks for significant physiologic effects to be small if they use the steroids for brief periods of time, many of these same athletes are unaware of the potential for habituation to the use of anabolic steroids. The result may be incessant use of steroids by an athlete who previously considered only short-term use. As we see athletes taking anabolic steroids for more prolonged periods, we are likely to see more severe medical consequences. Those who eventually do discontinue the steroids are dismayed to find that the improvements made with the steroids generally disappear and they have little to show for hours or even years of intense training beyond the psychological scars inherent with steroid use. Counseling of these athletes should focus on the potential adverse psychological consequences of anabolic steroid use and the significant risk for habituation.

摘要

运动员通常对可能用作增强运动能力辅助剂的物质有充分了解。这包括合成代谢类固醇和生长激素。幸运的是,生长激素的滥用受到其成本的限制,而且合成代谢类固醇对运动员更具吸引力。然而,关于其使用存在重大潜在不良反应,通过研究肢端肥大症综合征中已知的生长激素过量情况,能最好地理解这些不良反应。许多运动员不熟悉这种综合征,对生长激素过量的潜在后果进行教育,对于向考虑使用生长激素的运动员提供咨询很重要。虽然考虑使用合成代谢类固醇的运动员可能正确地认为,如果他们短期使用类固醇,出现重大生理影响的风险很小,但这些运动员中的许多人并未意识到对合成代谢类固醇使用产生习惯化的可能性。结果可能是,一名原本只考虑短期使用类固醇的运动员会持续使用。随着我们看到运动员使用合成代谢类固醇的时间更长,我们可能会看到更严重的医学后果。那些最终停止使用类固醇的人沮丧地发现,使用类固醇带来的改善通常消失了,而且除了使用类固醇所固有的心理创伤外,他们为长达数小时甚至数年的高强度训练几乎没有什么收获。对这些运动员的咨询应侧重于合成代谢类固醇使用潜在的不良心理后果以及产生习惯化的重大风险。

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