Gatchev O, Råstam L, Lindberg G, Gullberg B, Eklund G A, Törnberg S
Department of Community Health Sciences, Lund University, Malmö, Sweden.
Br J Cancer. 1993 Aug;68(2):425-7. doi: 10.1038/bjc.1993.353.
In a population-based study serum sialic acid level was examined in relation to subsequent development of central nervous system (CNS) tumours (229 cases). Significantly increased sialic acid concentration was found in men with a malignant CNS tumour diagnosed within 8 years of analysis, compared with corresponding matched controls. These findings suggest that the tumour existed at the time of examination which is supported by a negative linear association between sialic acid level and the time from screening to tumour diagnosis.
在一项基于人群的研究中，检测了血清唾液酸水平与随后中枢神经系统（CNS）肿瘤发生（229例）之间的关系。与相应的匹配对照组相比，在分析后8年内被诊断为恶性CNS肿瘤的男性中，发现唾液酸浓度显著升高。这些发现表明，在检查时肿瘤就已存在，这一点得到了唾液酸水平与从筛查到肿瘤诊断的时间之间呈负线性关联的支持。
