男性和女性中枢神经系统肿瘤与血清唾液酸浓度
Tumours of the central nervous system and serum sialic acid concentration in men and women.
作者信息
Gatchev O, Råstam L, Lindberg G, Gullberg B, Eklund G A, Törnberg S
机构信息
Department of Community Health Sciences, Lund University, Malmö, Sweden.
出版信息
Br J Cancer. 1993 Aug;68(2):425-7. doi: 10.1038/bjc.1993.353.
Abstract
In a population-based study serum sialic acid level was examined in relation to subsequent development of central nervous system (CNS) tumours (229 cases). Significantly increased sialic acid concentration was found in men with a malignant CNS tumour diagnosed within 8 years of analysis, compared with corresponding matched controls. These findings suggest that the tumour existed at the time of examination which is supported by a negative linear association between sialic acid level and the time from screening to tumour diagnosis.
摘要
在一项基于人群的研究中，检测了血清唾液酸水平与随后中枢神经系统（CNS）肿瘤发生（229例）之间的关系。与相应的匹配对照组相比，在分析后8年内被诊断为恶性CNS肿瘤的男性中，发现唾液酸浓度显著升高。这些发现表明，在检查时肿瘤就已存在，这一点得到了唾液酸水平与从筛查到肿瘤诊断的时间之间呈负线性关联的支持。
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本文引用的文献
1
A new method for measuring sialic acid levels in serum and its application to rheumatic fever.一种测量血清中唾液酸水平的新方法及其在风湿热中的应用。
J Clin Invest. 1957 Mar;36(3):449-55. doi: 10.1172/JCI103442.
2
Total and lipid-bound sialic acid in the cerebrospinal fluid of patients with brain tumors.脑肿瘤患者脑脊液中的总唾液酸和脂质结合唾液酸。
Anticancer Res. 1984 Jul-Oct;4(4-5):313-6.
3
Completeness of the Swedish Cancer Register. Non-notified cancer cases recorded on death certificates in 1978.瑞典癌症登记处的完整性。1978年死亡证明上记录的未报告癌症病例。
Acta Radiol Oncol. 1984;23(5):305-13. doi: 10.3109/02841868409136026.
4
[The clinical significance of sialic acid in the serum in benign and malignant disease].[血清唾液酸在良性和恶性疾病中的临床意义]
J Clin Chem Clin Biochem. 1987 Jul;25(7):423-30.
5
Pregnancy-related primary brain and spinal tumors.妊娠相关原发性脑和脊髓肿瘤。
Arch Neurol. 1987 Feb;44(2):209-15. doi: 10.1001/archneur.1987.00520140069020.
6
Sialic acid as a marker for differentiation between benign and malignant intracranial tumors.唾液酸作为鉴别颅内良恶性肿瘤的标志物。
Clin Chim Acta. 1988 Sep 15;176(3):251-7. doi: 10.1016/0009-8981(88)90184-2.
7
Relation between raised concentrations of fucose, sialic acid, and acute phase proteins in serum from patients with cancer: choosing suitable serum glycoprotein markers.癌症患者血清中岩藻糖、唾液酸浓度升高与急性期蛋白之间的关系：选择合适的血清糖蛋白标志物
J Clin Pathol. 1985 May;38(5):588-92. doi: 10.1136/jcp.38.5.588.
8
Sex steroids in human brain tumors and breast cancer.人类脑肿瘤和乳腺癌中的性类固醇。
Cancer. 1990 Feb 15;65(4):949-52. doi: 10.1002/1097-0142(19900215)65:4<949::aid-cncr2820650421>3.0.co;2-2.
9
[Diagnostic value of biochemical tumor markers in brain tumors. Review of the literature and own experience with serum analysis of sialic acid (NANA), carcinoembryonic antigen (CEA) and neuron-specific enolase (NSE)].[生化肿瘤标志物在脑肿瘤中的诊断价值。文献综述及自身对血清唾液酸（NANA）、癌胚抗原（CEA）和神经元特异性烯醇化酶（NSE）分析的经验]
Zentralbl Neurochir. 1990;51(3):129-37.
10
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BMJ. 1991 Jan 19;302(6769):143-6. doi: 10.1136/bmj.302.6769.143.
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