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法国拉阿格核废料后处理设施附近儿童白血病发病率

Childhood leukemia incidence in the vicinity of La Hague nuclear-waste reprocessing facility (France).

作者信息

Viel J F, Richardson S, Danel P, Boutard P, Malet M, Barrelier P, Reman O, Carré A

机构信息

Faculty of Medicine, Besançon, France.

出版信息

Cancer Causes Control. 1993 Jul;4(4):341-3. doi: 10.1007/BF00051336.

Abstract

The incidence of leukemia is examined in young people (aged under 25 years) living within a 35 km radius of the French nuclear-waste reprocessing plant operating in La Hague, Normandy. During the period 1978-90, a total of 23 cases was diagnosed, giving an incidence rate of 2.99 per 100,000 which is close to the expected rate. In the 'canton' in which the nuclear plant is located, three cases of leukemia were observed compared with 1.2 expected, giving a standardized incidence ratio of 2.5. This nonsignificant finding is compatible with no increased risk and also with a sevenfold excess risk. Therefore, it reinforces the necessity of conducting a case-control survey, which is now planned, to assess the part played by occupational radiation exposure in leukemia incidence for this French area.

摘要

对居住在诺曼底地区拉阿格的法国核废料后处理厂半径35公里范围内的25岁以下年轻人的白血病发病率进行了调查。在1978年至1990年期间,共诊断出23例病例,发病率为每10万人2.99例,接近预期发病率。在核电站所在的“县”,观察到3例白血病病例,而预期为1.2例,标准化发病率比为2.5。这一不显著的结果既与无风险增加相符,也与七倍的超额风险相符。因此,这进一步强化了进行病例对照研究的必要性,目前已计划开展此项研究,以评估职业性辐射暴露在该法国地区白血病发病率中所起的作用。

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