Hinke R M, Hu X, Stillman A E, Kim S G, Merkle H, Salmi R, Ugurbil K
Department of Radiology, University of Minnesota Medical School, Minneapolis 55455.
Neuroreport. 1993 Jun;4(6):675-8. doi: 10.1097/00001756-199306000-00018.
Conventional gradient-echo magnetic resonance imaging (MRI) at 4 Tesla was used successfully to study the activity of Broca's area during internal speech word generation in healthy right-handed volunteers. Activity was demonstrated in the internal gray matter surrounding the ascending ramus of the lateral sulcus, deep to the cortical surface representation of Broca's area, in all the subjects. These studies demonstrate the capability of functional MRI to non-invasively map language related cognitive functions. Such functional mapping has value for both the study of basic neuroscience and neurosurgical planning.
在4特斯拉的常规梯度回波磁共振成像(MRI)被成功用于研究健康右利手志愿者在内心言语单词生成过程中布罗卡区的活动。在所有受试者中,活动显示在外侧沟升支周围的内部灰质中,位于布罗卡区皮质表面表征的深部。这些研究证明了功能磁共振成像能够非侵入性地绘制与语言相关的认知功能。这种功能映射对于基础神经科学研究和神经外科手术规划都有价值。