Jelicks L A, Paul P K, O'Byrne E, Gupta R K
Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY.
J Magn Reson Imaging. 1993 Jul-Aug;3(4):565-8. doi: 10.1002/jmri.1880030403.
Viable bovine nasal cartilage was examined with magnetic resonance (MR) spectroscopy. Digestion of the proteoglycan matrix by papain or trypsin was accompanied by substantial changes in carbon-13, sodium-23, and hydrogen-1 MR spectra and relaxation parameters, with C-13 MR spectra showing the most pronounced changes. These results indicate the potential of MR spectroscopy (and imaging) for noninvasive evaluation of cartilage disease and monitoring of patients with degenerative joint diseases.
用磁共振（MR）波谱对存活的牛鼻软骨进行了检查。木瓜蛋白酶或胰蛋白酶对蛋白聚糖基质的消化伴随着碳-13、钠-23和氢磁共振波谱及弛豫参数的显著变化，其中碳-13磁共振波谱显示出最明显的变化。这些结果表明磁共振波谱（和成像）在软骨疾病的无创评估及退行性关节疾病患者监测方面具有潜力。
