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低强度超声导致微管解聚。

Disassembly of microtubules due to low intensity ultrasound.

作者信息

Adler J, Necas O, Hrazdira I

机构信息

Department of Biology, Faculty of Medicine, Masaryk University, Brno.

出版信息

Folia Biol (Praha). 1993;39(1):55-7.

PMID:8348986
Abstract

HeLa and MCF cell monolayers growing on glass cover-slips were sonicated using continuous wave ultrasound at low intensity levels approaching diagnostic conditions. The disassembly of cytoplasmic microtubules immediately after sonication was demonstrated using indirect immunofluorescence. The recovery from exposure to ultrasound, i.e. the reassembly of microtubules, was observed in the cultured cells 2 h after the sonication was discontinued.

摘要

在接近诊断条件的低强度水平下,使用连续波超声对生长在玻璃盖玻片上的HeLa细胞和MCF细胞单层进行超声处理。使用间接免疫荧光法证明了超声处理后细胞质微管立即发生解体。在超声处理停止2小时后,在培养的细胞中观察到了从超声暴露中的恢复情况,即微管的重新组装。

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