参与核苷补救途径的梨支原体基因的鉴定。
Identification of Mycoplasma pirum genes involved in the salvage pathways for nucleosides.
作者信息
Tham T N, Ferris S, Kovacic R, Montagnier L, Blanchard A
机构信息
Departement du SIDA et des rétrovirus, Oncologie Virale, Institut Pasteur, Paris, France.
出版信息
J Bacteriol. 1993 Aug;175(16):5281-5. doi: 10.1128/jb.175.16.5281-5285.1993.
Abstract
Genes encoding enzymes involved in the salvage pathway for nucleosides have been cloned and sequenced from the mollicute Mycoplasma pirum. One of them, encoding deoxyriboaldolase, was functionally identified by complementation of an Escherichia coli mutant. These genes are clustered, suggesting an operon organization, and they are immediately followed by the putative gene for the triose phosphate isomerase, an enzyme used during glycolysis.
摘要
编码参与核苷补救途径的酶的基因已从柔膜菌属的梨支原体中克隆并测序。其中一个编码脱氧核糖醛缩酶的基因通过对大肠杆菌突变体的互补作用进行了功能鉴定。这些基因成簇排列，表明存在操纵子结构，并且在它们之后紧接着是磷酸丙糖异构酶的推定基因，磷酸丙糖异构酶是糖酵解过程中使用的一种酶。
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