Gentzkow G D
Staodyn, Inc., Longmont, Colorado.
J Dermatol Surg Oncol. 1993 Aug;19(8):753-8. doi: 10.1111/j.1524-4725.1993.tb00420.x.
Numerous human and animal efficacy studies have demonstrated that electrical stimulation of the correct charge, density and total energy causes dramatically improved healing of dermal wounds. The investigations of biological actions (in vitro, animal, and human) demonstrate several effects that go a long way to explaining why electrical stimulation works.
To discuss recent research and advances in electrical stimulation of wound healing.
Based on the latest scientific understanding of the wound healing process, one would expect a beneficial outcome from a therapy what decreases edema, debrides necrotic tissue, attracts neutrophils and macrophages, stimulates receptor sites for growth factors, stimulates growth of fibroblasts and granulation tissue, increases blood flow, stimulates neurite growth, induces epidermal cell migration, prevents post-ischemic oxygen radical-mediated damage, inhibits bacteria, and reduces numbers of mast cells.
Taken together, the efficacy studies and the "mechanism of action" studies provide compelling, scientific evidence that electrical stimulation is safe and effective for promoting the healing of dermal wounds.
大量人体和动物功效研究表明，以正确的电荷、密度和总能量进行电刺激可显著促进皮肤伤口愈合。对生物作用（体外、动物和人体）的研究表明了几种作用，这些作用在很大程度上解释了电刺激为何有效。
探讨伤口愈合电刺激方面的最新研究及进展。
基于对伤口愈合过程的最新科学认识，人们预期一种能减轻水肿、清创坏死组织、吸引中性粒细胞和巨噬细胞、刺激生长因子受体位点、刺激成纤维细胞和肉芽组织生长、增加血流量、刺激神经突生长、诱导表皮细胞迁移、预防缺血后氧自由基介导的损伤、抑制细菌并减少肥大细胞数量的治疗方法会产生有益效果。
综合来看，功效研究和“作用机制”研究提供了令人信服的科学证据，表明电刺激在促进皮肤伤口愈合方面是安全有效的。
