Lelièvre J C, Delgallo H, Lacombe C, Bucherer C
Département de Biophysique, Université Paris VI.
J Mal Vasc. 1993;18(2):153-6.
A clinical hemoviscosiSImeter is presented. It is a Couette type viscometer which is automatic and driven by a microcomputer. It was designed and realized in the laboratory. The measurement of blood viscosity requires 1 ml of anticoagulated blood adjusted at 45% of hematocrit. Experiments are performed at a constant temperature (37 degrees C) according to a well-established protocol: gentle mixing of the blood sample followed by a 3 minute rest just before each of the following measurement modes begins. Under steady state flow conditions, 12 viscosity measurements are realized in a range of shear stress rate step of 1 s-1 is applied. The elastothixotropic response of the blood sample is then obtained. Such a hemorheological test, called "hemorheogram", requires 15 minutes. Given to the clinician, the hemorheogram results include the absolute blood viscosities at the shear stress rates of 0.1 s-1, 1 s-1, 10 s-1, 70 s-1, the thixotropy index and the plasma viscosity. Finally, results to be kept in the laboratory files consist of the whole data issued from the patient hemorheogram including the relative blood viscosities (blood viscosity/plasma viscosity) at the same shear strers rate values.
介绍了一种临床血液粘度计。它是一种库埃特型粘度计，由微型计算机驱动，具有自动化功能。该仪器是在实验室设计并实现的。测量血液粘度需要1毫升抗凝血液，血细胞比容调整为45%。实验在恒温（37摄氏度）条件下按照既定方案进行：在每次以下测量模式开始前，先轻轻混合血样，然后静置3分钟。在稳态流动条件下，在1 s-1的剪切应力速率步长范围内进行12次粘度测量，随后获得血样的弹触变性响应。这样一种血液流变学测试，即“血液流变图”，需要15分钟。提供给临床医生的血液流变图结果包括剪切应力速率为0.1 s-1、1 s-1、10 s-1、70 s-1时的绝对血液粘度、触变性指数和血浆粘度。最后，保存在实验室文件中的结果包括患者血液流变图产生的所有数据，包括相同剪切应力速率值下的相对血液粘度（血液粘度/血浆粘度）。
