de Boccard G A, Rochat C H
Ann Urol (Paris). 1993;27(3):152-5.
The treatment of erectile failure has developed rapidly over the last decade with the introduction of intracavernosal self injection therapy, first with phenoxybenzamine, then with papaverine and paraverine-phentolamine. These drugs are now progressively replaced by prostaglandin E1 mainly because of its efficacy and fewer side effects. Prostaglandin E1 can induce a rigid erection even in case of severe arteriopathy and offers an excellent alternative to a prosthetic implant.
在过去十年中，随着海绵体内自我注射疗法的引入，勃起功能障碍的治疗发展迅速。最初使用苯氧苄胺，随后使用罂粟碱和罂粟碱 - 酚妥拉明。这些药物现在逐渐被前列腺素E1取代，主要是因为其疗效好且副作用较少。即使在严重动脉病变的情况下，前列腺素E1也能诱导出坚挺的勃起，为假体植入提供了极佳的替代方案。
