Altucci P, Abbate G
Dipartimento di Internistica Clinica, Facoltà di Medicina e Chirurgia, II Università, Napoli.
Recenti Prog Med. 1993 Jul-Aug;84(7-8):551-69.
Authors point out, on the basis of literature and of their own experience, the following aspects of Mycoplasma infections: 1) Genetical and biological progresses, especially related to pathogenetic aspects and diagnostic procedures. 2) Recent clinical and diagnostic findings of M. pneumoniae infections: "bacteria-like" pulmonary presentations by mycoplasmas (and, on the contrary, "virus-like" pulmonary presentations by bacteria); atypical kinds of pulmonary presentations by mycoplasmas; role of autoimmunity in extrapulmonary involvement. 3) Relationship among mycoplasmas, immune system and autoimmune diseases, with particular regard to animal models and to the Mycoplasma "superantigen". 4) Appearance of new pathogens and of a new spectrum of Mycoplasma infections: genito-urinary involvement by Ureaplasma urealyticum and by M. Hominis; relationship between Mycoplasma spp. and HIV infection.
作者基于文献及自身经验，指出支原体感染的以下几个方面：1）遗传学和生物学进展，特别是与发病机制及诊断程序相关的方面。2）肺炎支原体感染的近期临床及诊断发现：支原体的“类细菌”肺部表现（相反，细菌的“类病毒”肺部表现）；支原体的非典型肺部表现；自身免疫在肺外受累中的作用。3）支原体、免疫系统与自身免疫性疾病之间的关系，尤其涉及动物模型及支原体“超抗原”。4）新病原体的出现及支原体感染新谱：解脲脲原体和人型支原体引起的泌尿生殖系统受累；支原体属与HIV感染之间的关系。
