Fukunaga K, Ninomiya M, Oohara Y, Kusunose K, Okamura Y, Nagasaki H, Ishino S, Kadota K
Chuo Meat Inspection Office, Kochi, Japan.
J Vet Med Sci. 1993 Jun;55(3):465-7. doi: 10.1292/jvms.55.465.
Lymphoplasmacytic lymphoma found in a 6-year-old Anglo-Arabian stallion was investigated histologically, immunohistochemically and ultrastructurally. The animal showed a large mediastinal mass and generalized lymph node involvement. The neoplastic cells were in various differentiation stages of small lymphocyte, centrocyte, centroblast, immunoblast and plasma cell. Some neoplastic cells showed positive cytoplasmic reactivity for mu and lambda chains. There were well developed rough endoplasmic reticulum (RER) and Golgi complexes in plasmacytoid cells, and slightly developed RER or a few long strands of RER in medium-sized to large lymphoid cells. These findings suggest that this neoplasm is of B-cell origin.
对一匹6岁的英阿拉伯种公马身上发现的淋巴浆细胞性淋巴瘤进行了组织学、免疫组织化学和超微结构研究。该动物表现为纵隔巨大肿块和全身淋巴结受累。肿瘤细胞处于小淋巴细胞、中心细胞、中心母细胞、免疫母细胞和浆细胞的不同分化阶段。一些肿瘤细胞的细胞质对μ链和λ链呈阳性反应。浆细胞样细胞中有发达的粗面内质网（RER）和高尔基体，中等大小至大淋巴细胞中的RER发育轻微或有几条RER长链。这些发现表明该肿瘤起源于B细胞。
