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大鼠下丘脑-神经垂体系统中的胰岛素样免疫反应性(IRI):脱水和出血的影响。

Insulin-like immunoreactivity (IRI) in the rat hypothalamo-neurohypophysial system: effect of dehydration and haemorrhage.

作者信息

Stempniak B, Guzek J W

机构信息

Department of Pathophysiology, School of Medicine, Lodz, Poland.

出版信息

J Physiol Pharmacol. 1993 Jun;44(2):155-9.

PMID:8358052
Abstract

Hypothalamic IRI was not affected in haemorrhaged rats, but diminished considerably in the dehydrated ones. In the neurohypohysis, IRI was distinctly higher both in dehydrated and haemorrhaged rats, i.e., under disorders which stimulated vasopressin and/or oxytocin release. It is suggested that insulin-like substance(s) may be someway involved in regulation of vasopressin or oxytocin secretion.

摘要

下丘脑胰岛素反应性在出血大鼠中未受影响,但在脱水大鼠中显著降低。在神经垂体中,无论是脱水大鼠还是出血大鼠,胰岛素反应性都明显较高,即在刺激抗利尿激素和/或催产素释放的紊乱情况下。提示胰岛素样物质可能以某种方式参与抗利尿激素或催产素分泌的调节。

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