Ito Y, Inoue M, Liu S Q, Imanishi Y
Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Japan.
J Biomed Mater Res. 1993 Jul;27(7):901-7. doi: 10.1002/jbm.820270709.
A cell growth factor protein (insulin) and/or a cell-adhesion protein (fibronectin) were immobilized on surface-hydrolyzed poly(methyl methacrylate) membranes. The growth of mouse fibroblast cells STO was accelerated by the immobilized insulin. This acceleration was enhanced by introduction of spacer arms. Coimmobilization of insulin and fibronectin was very effective for the acceleration of cell growth.
一种细胞生长因子蛋白（胰岛素）和/或一种细胞粘附蛋白（纤连蛋白）被固定在表面水解的聚甲基丙烯酸甲酯膜上。固定化的胰岛素加速了小鼠成纤维细胞STO的生长。通过引入间隔臂，这种加速作用得到增强。胰岛素和纤连蛋白的共固定化对细胞生长的加速非常有效。
